Catheter-directed thrombolysis for submassive pulmonary embolism in children: A case series

被引：9

作者：

Belsky, Jennifer ^{[1
,2
]}

Warren, Patrick ^{[2
,3
]}

Stanek, Joseph ^{[4
]}

Kumar, Riten ^{[1
,2
]}

机构：

[1] Nationwide Childrens Hosp, Columbus, OH USA

[2] Ohio State Univ, Dept Pediat, Columbus, OH 43210 USA

[3] Nationwide Childrens Hosp, Div Intervent Radiol, Columbus, OH USA

[4] Nationwide Childrens Hosp, Div Biostat, Columbus, OH USA

来源：

PEDIATRIC BLOOD & CANCER | 2020年 / 67卷 / 04期

关键词：

pulmonary embolism; thrombolysis; venous thromboembolism; VENOUS THROMBOEMBOLISM; UNITED-STATES; RISK; COMMUNICATION; MANAGEMENT; THROMBOSIS; THERAPY; DISEASE; TRIAL; SSC;

D O I：

10.1002/pbc.28144

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Incidence of venous thromboembolism, including pulmonary embolism (PE), continues to rise in children. Optimum management of submassive PE is unclear. The principal objective of this retrospective study was to investigate the radiological and clinical outcomes in children with submassive PE treated with catheter-directed thrombolysis (CDT). Five patients underwent six episodes of CDT. No patient developed major/clinically relevant non-major bleeding. Most patients had complete radiological thrombus resolution and no patient had evidence of chronic thromboembolic pulmonary hypertension. There is an urgent need for larger prospective cohort studies/randomized controlled trials to investigate the role of CDT in pediatric PE.

引用

页数：5

共 27 条

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