Noise performance design of CMOS preamplifier for the active semiconductor neural probe

被引：8

作者：

Kim, KH ^{[1
]}

Kim, SJ ^{[1
]}

机构：

[1] Seoul Natl Univ, Sch Elect Engn, Kwanak Gu, Seoul 151742, South Korea

来源：

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING | 2000年 / 47卷 / 08期

关键词：

active neural probe; CMOS; differential amplifier; extracellular recording; signal-to-noise ratio;

D O I：

10.1109/10.855938

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A systematic design guideline is presented for the noise performance of preamplifier for semiconductor neural probe which contains on-chip electronic circuitry, The overall signal-to-noise ratio (SNR) is calculated considering the spectral characteristics of the measured extracellular action potential and the low-frequency noise spectrum of the CMOS device from typical fabrication processes. An analytical expression of the output noise power is derived, and utilized to tailor the frequency response and device parameters which are controllable by the circuit designer, An analysis of the output SNR of a two stage CMOS differential amplifier is given and the major factors which have significant effects on the SNR are determined, We showed that a little deviation of the input device sizes and transconductance ratio from the optimal values can significantly deteriorate the SNR. Quantitative information of the preamplifier circuit parameters for satisfactory noise performance is provided.

引用

页码：1097 / 1105

页数：9

共 29 条

[1]

ALIZADEHTAHERI B, 1995, P 6 INT C SOL STAT S, P67

[2]

[Anonymous], 1974, TRANSDUCERS BIOMEDIC

[3] OPTIMAL DETECTION, CLASSIFICATION, AND SUPERPOSITION RESOLUTION IN NEURAL WAVE-FORM RECORDINGS [J].

BANKMAN, IN ;

JOHNSON, KO ;

SCHNEIDER, W .

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1993, 40 (08) :836-841

[4] SOLID-STATE ELECTRODES FOR MULTICHANNEL MULTIPLEXED INTRACORTICAL NEURONAL RECORDING [J].

BEMENT, SL ;

WISE, KD ;

ANDERSON, DJ ;

NAJAFI, K ;

DRAKE, KL .

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1986, 33 (02) :230-241

[5]

BERTAILS JC, 1979, IEEE J SOLID STA AUG, P773

[6] Detection, classification, and superposition resolution of action potentials in multiunit single-channel recordings by an on-line real-time neural network [J].

Chandra, R ;

Optican, LM .

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1997, 44 (05) :403-412

[7] FLICKER NOISE IN CMOS TRANSISTORS FROM SUBTHRESHOLD TO STRONG INVERSION AT VARIOUS TEMPERATURES [J].

CHANG, JM ;

ABIDI, AA ;

VISWANATHAN, CR .

IEEE TRANSACTIONS ON ELECTRON DEVICES, 1994, 41 (11) :1965-1971

[8]

Desel T, 1996, 1996 2ND INTERNATIONAL CONFERENCE ON ASIC, PROCEEDINGS, P115, DOI 10.1109/ICASIC.1996.562765

[9]

DORMAN MG, 1985, IEEE J SOLID STA DEC, P1185

[10] Circuit techniques for reducing the effects of op-amp imperfections: Autozeroing, correlated double sampling, and chopper stabilization [J].

Enz, CC ;

Temes, GC .

PROCEEDINGS OF THE IEEE, 1996, 84 (11) :1584-1614

← 1 2 3 →