Parity, tubal sterilization, hysterectomy and risk of primary fallopian tube carcinoma in Finland, 1975-2004

被引:20
作者
Riska, Annika
Sund, Reijo
Pukkala, Eero
Gissler, Mika
Leminen, Arto
机构
[1] Univ Helsinki, Cent Hosp, Dept Obstet & Gynaecol, Helsinki, Finland
[2] STAKES, Natl Res & Dev Ctr Welf & Hlth, Helsinki, Finland
[3] Finnish Canc Registry, Inst Stat & Epidemiol Canc Res, FIN-00170 Helsinki, Finland
关键词
PFTC; tubal sterilization; hysterectomy; parity;
D O I
10.1002/ijc.22491
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We studied the possible relationship among parity, female sterilization, hysterectomy and the risk of primary fallopian tube carcinoma (PFTC) in a case-control study in Finland in cases occurring between 1975 and 2004. A total of 573 PFTC cases were identified from the Finnish Cancer Registry, and 10 age-matched controls per case were randomly selected from the Finnish Central Population Registry. In multivariate analysis (including 189 PFTC cases and 1764 controls) parity was protective: the odds ratio (OR) for 1-2 deliveries was 0.63 (95% CI 0.44-0.91) and for >= 3 deliveries, 0.32 (95% CI 0.19-0.52). The OR for sterilization was 0.74 (95% CI 0.42-1.30) and for hysterectomy 1.27 (95% CI 0.73-2.21). Our findings suggest a possible hormonal background as regards the development of PFTC. (c) 2006 Wiley-Liss, Inc.
引用
收藏
页码:1351 / 1354
页数:4
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