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Pyrrolizidine alkaloids from Senecio roseus and Senecio helodes
被引:21
作者:
Pérez-Castorena, AL
Arciniegas, A
Castro, A
Villaseñor, JL
Toscano, RA
de Vivar, AR
机构:
[1] Univ Nacl Autonoma Mexico, Inst Quim, Mexico City 04510, DF, Mexico
[2] Univ Nacl Autonoma Mexico, Inst Biol, Mexico City 04510, DF, Mexico
来源:
JOURNAL OF NATURAL PRODUCTS
|
1997年
/
60卷
/
12期
关键词:
D O I:
10.1021/np9702289
中图分类号:
Q94 [植物学];
学科分类号:
071001 ;
摘要:
Two new 13-membered macrocylic pyrrolizidine alkaloids, (13R)-13-hydroxyretroisosenine (2b) and (12S)-12-hydroxyretroisosenine (2c), have been isolated from Senecio roseus and Senecio helodes. Their structures were established il om spectral and chemical studies including 2D NMR. The hydrochloride of retroisosenine (2a-HCl) was also isolated, and its absolute configuration was determined by X-ray diffraction analysis.
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页码:1322 / 1325
页数:4
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