Findings of clinical trials that evaluate the impact of medical therapies on progression of atherosclerosis

被引：1

作者：

Lavoie, Andrea ^{[1
]}

Uno, Kiyoko ^{[1
]}

Bayturan, Ozgur ^{[1
]}

Nicholls, Stephen J. ^{[1
]}

机构：

[1] Cleveland Clin, Dept Cardiovasc Med, Inst Heart & Vasc, Cleveland, OH 44195 USA

来源：

CURRENT MEDICAL RESEARCH AND OPINION | 2010年 / 26卷 / 03期

关键词：

Atherosclerosis; Clinical trials; Imaging; Prevention; Risk factors; CORONARY-ARTERY-DISEASE; HIGH-DENSITY-LIPOPROTEIN; LIPID-LOWERING THERAPY; RANDOMIZED CONTROLLED-TRIAL; DOUBLE-BLIND TRIAL; BEAM COMPUTED-TOMOGRAPHY; TYPE-2; DIABETES-MELLITUS; EXTENDED-RELEASE NIACIN; STATIN THERAPY; FAMILIAL HYPERCHOLESTEROLEMIA;

D O I：

10.1185/03007990903547616

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Arterial wall imaging has been increasingly employed in clinical trials to evaluate the impact of medical therapies on progression of atherosclerosis. Scope: A selective overview of major findings from clinical trials that assessed the impact of medical therapies on atherosclerosis progression. Findings: Targeting established risk factors including LDL cholesterol, HDL cholesterol and blood pressure has a beneficial impact on disease progression. Conclusion: As a result, vascular imaging has been employed in the early evaluation of experimental therapies.

引用

页码：745 / 751

页数：7

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