Social interactions in the Burkholderia cepacia complex: biofilms and quorum sensing

被引:40
|
作者
Coenye, Tom [1 ]
机构
[1] Univ Ghent, Lab Pharmaceut Microbiol, B-9000 Ghent, Belgium
关键词
antimicrobial resistance; biofilm; Burkholderia cepacia; complex; quorum sensing; PSEUDOMONAS-AERUGINOSA BIOFILMS; TOLERANT PERSISTER CELLS; TRANSITION-METAL GALLIUM; CYSTIC-FIBROSIS PATIENTS; IN-VITRO; ANTIBIOTIC-RESISTANCE; EXOPOLYSACCHARIDE PRODUCTION; HYDROGEN-PEROXIDE; SIGMA-FACTOR; STAPHYLOCOCCUS-AUREUS;
D O I
10.2217/FMB.10.68
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Burkholderia cepacia complex bacteria are opportunistic pathogens that cause respiratory tract infections in susceptible patients, mainly people with cystic fibrosis. There is convincing evidence that B. cepacia complex bacteria can form biofilms, not only on abiotic surfaces (e.g., glass and plastics), but also on biotic surfaces such as epithelial cells, leading to the suggestion that biofilm formation plays a key role in persistent infection of cystic fibrosis lungs. This article presents an overview of the molecular mechanisms involved in B. cepacla complex biofilm formation, the increased resistance of sessile B. cepacia complex cells and the role of quorum sensing in B. cepacia complex biofilm formation.
引用
收藏
页码:1087 / 1099
页数:13
相关论文
共 50 条
  • [1] Quorum sensing in the Burkholderia cepacia complex
    Venturi, V
    Friscina, A
    Bertani, I
    Devescovi, G
    Aguilar, C
    RESEARCH IN MICROBIOLOGY, 2004, 155 (04) : 238 - 244
  • [2] Distribution of quorum-sensing genes in the Burkholderia cepacia complex
    Lutter, E
    Lewenza, S
    Dennis, JJ
    Visser, MB
    Sokol, PA
    INFECTION AND IMMUNITY, 2001, 69 (07) : 4661 - 4666
  • [3] Quorum sensing signals in Burkholderia cepacia
    Quan, Chun-Shan
    Wang, Jian-Hua
    Li, Xin
    Fan, Sheng-Di
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 237 : 81 - 81
  • [4] Quorum Sensing and Bacterial Social Interactions in Biofilms
    Li, Yung-Hua
    Tian, Xiaolin
    SENSORS, 2012, 12 (03) : 2519 - 2538
  • [5] Identification of quorum-sensing-regulated genes of Burkholderia cepacia
    Aguilar, C
    Friscina, A
    Devescovi, G
    Kojic, M
    Venturi, V
    JOURNAL OF BACTERIOLOGY, 2003, 185 (21) : 6456 - 6462
  • [6] Quorum sensing in Burkholderia cepacia:: Identification of the LuxRI homologs CepRI
    Lewenza, S
    Conway, B
    Greenberg, EP
    Sokol, PA
    JOURNAL OF BACTERIOLOGY, 1999, 181 (03) : 748 - 756
  • [7] Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex
    Suppiger, Angela
    Schmid, Nadine
    Aguilar, Claudio
    Pessi, Gabriella
    Eberl, Leo
    VIRULENCE, 2013, 4 (05) : 400 - 409
  • [8] Production of the antifungal compound pyrrolnitrin is quorum sensing-regulated in members of the Burkholderia cepacia complex
    Schmidt, Silvia
    Blom, Judith F.
    Pernthaler, Jakob
    Berg, Gabriele
    Baldwin, Adam
    Mahenthiralingam, Eshwar
    Eberl, Leo
    ENVIRONMENTAL MICROBIOLOGY, 2009, 11 (06) : 1422 - 1437
  • [9] A quorum-quenching a approach to investigate the conservation of quorum-sensing-regulated functions within the Burkholderia cepacia complex
    Wopperer, J
    Cardona, ST
    Huber, B
    Jacobi, CA
    Valvano, MA
    Eberl, L
    APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2006, 72 (02) : 1579 - 1587
  • [10] Biofilms, flocculation and quorum sensing in yeast: from molecular to social interactions
    Verstrepen, K. J.
    FEBS JOURNAL, 2009, 276 : 73 - 73