Neurologic Manifestations of Systemic Lupus Erythematosus in Children and Adults

被引:154
作者
Muscal, Eyal [2 ]
Brey, Robin L. [1 ]
机构
[1] Univ Texas Hlth Sci Ctr San Antonio, Dept Neurol, San Antonio, TX 78229 USA
[2] Baylor Coll Med, Div Pediat Rheumatol, Texas Childrens Hosp, Houston, TX 77030 USA
关键词
Collagen vascular disease; Systemic lupus erythematosus; Neurologic disease; Autoantibodies; Cognitive dysfunction; INTERNATIONAL INCEPTION COHORT; STEM-CELL TRANSPLANTATION; BLOOD-BRAIN-BARRIER; NEUROPSYCHIATRIC MANIFESTATIONS; CHILDHOOD-ONSET; WHITE-MATTER; COGNITIVE DYSFUNCTION; AUTOIMMUNE-DISEASE; NMDA RECEPTORS; ANTIBODIES;
D O I
10.1016/j.ncl.2009.09.004
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Among the collagen vascular diseases neurologic manifestations have been most commonly recognized and well-studied in systemic lupus erythematosus (SLE, lupus). Neurologic manifestations are less prevalent in other systemic inflammatory and autoimmune disorders. This review focuses on the clinical presentation, pathophysiology, and treatment strategies of neuropsychiatric lupus (NPSLE) in children and adults.
引用
收藏
页码:61 / +
页数:14
相关论文
共 67 条
  • [1] The blood-brain barrier in systemic lupus erythematosus
    Abbott, NJ
    Mendonça, LLF
    Dolman, DEM
    [J]. LUPUS, 2003, 12 (12) : 908 - 915
  • [2] Neuropsychiatric systemic lupus erythematosus - Correlation of brain MR imaging, CT, and SPECT
    Abreu, MR
    Jakosky, A
    Folgerini, M
    Brenol, JCT
    Xavier, RM
    Kapczinsky, F
    [J]. CLINICAL IMAGING, 2005, 29 (03) : 215 - 221
  • [3] Increased serum matrix metalloproteinase 9 levels in systemic lupus erythematosus patients with neuropsychiatric manifestations and brain magnetic resonance imaging abnormalities
    Ainiala, H
    Hietaharju, A
    Dastidar, P
    Loukkola, J
    Lehtimäki, T
    Peltola, J
    Korpela, M
    Heinonen, T
    Nikkari, ST
    [J]. ARTHRITIS AND RHEUMATISM, 2004, 50 (03): : 858 - 865
  • [4] The prevalence of neuropsychiatric syndromes in systemic lupus erythematosus
    Ainiala, H
    Loukkola, J
    Peltola, J
    Korpela, M
    Hietaharju, A
    [J]. NEUROLOGY, 2001, 57 (03) : 496 - 500
  • [5] [Anonymous], ARTHRITIS RHEUM
  • [6] Hippocampal atrophy in systemic lupus erythematosus
    Appenzeller, S.
    D Carnevalle, A.
    Li, L. M.
    Costallat, L. T. L.
    Cendes, F.
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2006, 65 (12) : 1585 - 1589
  • [7] Cerebral and corpus callosum atrophy in systemic lupus erythematosus
    Appenzeller, S
    Rondina, JM
    Li, LM
    Costallat, LTL
    Cendes, F
    [J]. ARTHRITIS AND RHEUMATISM, 2005, 52 (09): : 2783 - 2789
  • [8] Controlled clinical trial of IV cyclophosphamide versus IV methylprednisolone in severe neurological manifestations in systemic lupus erythematosus
    Barile-Fabris, L
    Ariza-Andraca, R
    Olguín-Ortega, L
    Jara, LJ
    Fraga-Mouret, A
    Miranda-Limón, JM
    de la Mata, JF
    Clark, P
    Vargas, F
    Alcocer-Varela, J
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2005, 64 (04) : 620 - 625
  • [9] BEIMONT HM, 1996, ARTHRITIS RHEUM, V39, P9
  • [10] Neuropsychiatric involvement in pediatric systemic lupus erythematosus
    Benseler, S. M.
    Silverman, E. D.
    [J]. LUPUS, 2007, 16 (08) : 564 - 571