Facile synthesis of bright yellow fluorescent nitrogen-doped carbon quantum dots and their applications to an off-on probe for highly sensitive detection of methimazole

被引：29

作者：

Yu, Chunhe ^{[1
]}

Qin, Dongmiao ^{[1
]}

Jiang, Xiaohua ^{[1
]}

Zheng, Xiangfei ^{[1
]}

Deng, Biyang ^{[1
]}

机构：

[1] Guangxi Normal Univ, Sch Chem & Pharmaceut Sci, State Key Lab Chem & Mol Engn Med Resources, Guilin 541004, Peoples R China

来源：

MICROCHEMICAL JOURNAL | 2021年 / 168卷

基金：

中国国家自然科学基金;

关键词：

Carbon quantum dot; Lettuce leaf; Methimazole; Fluorescent probe; Mouse plasma; SPECTROPHOTOMETRIC DETERMINATION; URINE; NANOPARTICLES; THYREOSTATS; SAMPLES; SENSOR;

D O I：

10.1016/j.microc.2021.106480

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In this work, bright yellow fluorescent nitrogen-doped carbon quantum dots (YN-CQDs) are produced by a facile, inexpensive and eco-friendly hydrothermal technique using extract of chlorophyll from lettuce leaf as precursor. The quantum yield (QY) of as-synthesized YN-CQDs was up to 38%, which was higher than the previously reported quantum yield of most CQDs prepared using other biomass. Silver ion (Ag+) can covalently bond with carboxyl, hydroxyl and amino groups on the surface of YN-CQDs and quench the fluorescence of YN-CQDs through static quenching. Upon addition of methimazole (MZ) to the YN-CQDs/Ag+ dispersion system, Ag+ releases from the YN-CQDs/Ag+ complex due to the high affinity of MZ for Ag+ and the quenched fluorescence of the YN-CQDs was recovered. Hence, we developed an off-on sensing method for the detection of MZ using YN-CQDs/Ag+ as a fluorescent probe. Under optimal conditions, with addition of MZ, the fluorescence recovery of YN-CQDs/Ag+ system happens with a good linearity in the range of 0.003 similar to 60 mu mol/L and a detection limit of 0.8 nmol/L. The YN-CQDs/Ag+ system exhibited good MZ determination performance. The established off-on fluorescence sensing platform was successfully employed for detecting MZ in mouse plasma.

引用

页数：7