Palladium-catalyzed C-H alkylation of 2-phenylpyridines with alkyl iodides

被引:16
作者
Wang, Xiaoling
Ji, Xiaoming
Shao, Changdong
Zhang, Yu
Zhang, Yanghui [1 ]
机构
[1] Tongji Univ, Sch Chem Sci & Engn, 1239 Siping Rd, Shanghai 200092, Peoples R China
基金
中国国家自然科学基金;
关键词
CARBON-HYDROGEN BONDS; C(SP(3))-H BONDS; DIRECTED ALKYLATION; BENZOIC-ACIDS; HALIDES; ACTIVATION; LIGAND; FUNCTIONALIZATION; ARYLATION; NORBORNENE;
D O I
10.1039/c7ob01232b
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Palladium-catalyzed C-H alkylation reaction of 2-phenylpyridines with alkyl iodides has been successfully developed. The palladacycles obtained from 2-phenylpyridines should act as the key intermediates in the alkylation reaction.
引用
收藏
页码:5616 / 5624
页数:9
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