A multifunctional two-photon fluorescent probe for detecting H2S in wastewater and GSH in vivo

被引：33

作者：

Yu, Bin ^{[1
,2
]}

Chen, Chunyang ^{[1
,2
]}

Ru, Jiaxi ^{[3
,4
]}

Luo, Weifang ^{[1
,2
]}

Liu, Weisheng ^{[1
,2
]}

机构：

[1] Lanzhou Univ, Coll Chem & Chem Engn, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Peoples R China

[2] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

[3] Chinese Acad Agr Sci, Lanzhou Vet Res Inst, State Key Lab Vet Etiol Biol, Xujiaping 1, Lanzhou 730046, Gansu, Peoples R China

[4] Chinese Acad Agr Sci, Lanzhou Vet Res Inst, Minist Agr, Key Lab Anim Virol, Xujiaping 1, Lanzhou 730046, Gansu, Peoples R China

来源：

TALANTA | 2018年 / 188卷

基金：

中国国家自然科学基金;

关键词：

Coumarin; Fluorescent probe; Thiols; Hydrogen sulfide; Bioimaging; HIGHLY SELECTIVE DETECTION; HYDROGEN-SULFIDE; LIVING CELLS; NUCLEOPHILIC-SUBSTITUTION; GLUTATHIONE; CYSTEINE; HOMOCYSTEINE; RECOGNITION; FABRICATION; LEVEL;

D O I：

10.1016/j.talanta.2018.05.076

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel turn-on fluorescent probe, which coumarin-fused coumarin was used as fluorophore to link with 2, 4-dinitrodiphenyl ether moiety that has high selectivity and sensitivity for H2S and thiols, was designed and synthesized. Our probe YB can sensitively react with H2S and GSH to release free fluorophore with strong fluorescence signals. The probe YB could use as a significant molecular imaging tool to study the endogenous GSH in living cell and a practical detector for H2S in the papermaking wastewater.

引用

页码：370 / 377

页数：8

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