Pigmented choroid plexus carcinoma: A cytogenetic and ultrastructural study

被引：6
作者：
Dobin, SM [1 ]
Donner, LR [1 ]
机构：
[1] TEXAS A&M UNIV, CTR HLTH SCI,COLL MED,SHERWOOD & BRINDLEY FDN, SCOTT & WHITE MEM HOSP & CLIN, TEMPLE, TX 76508 USA
来源：
CANCER GENETICS AND CYTOGENETICS | 1997年 / 96卷 / 01期
关键词：
D O I：
10.1016/S0165-4608(96)00264-6
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A pigmented choroid plexus carcinoma was studied. The pigment was Fontana-positive, and the neoplastic cells focally expressed melanosomal marker HMB45 and contained probable aberrant melanosomes. The tumor was composed of two pseudodiploid clones, having the karyotypes 46,Xu,inv(4)(q12q35),t(6;15)(q21;q22),inv(7)(p11.2q22),t(19;22)(q13.4;q11.2)[15]/46,XY,t(4;14)(q31.1; p11.2),t(12;13)(p11.2;q34)[6]. The available data seem to indicate that rearrangements of 7p11-12, 9q11-12, 15q22, and 19q13.4 may play a role in the development of choroid plexus carcinomas. (C) Elsevier Science Inc., 1997.
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页码：37 / 41
页数：5
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