Germacranolides from Anvillea radiata

被引：49

作者：

El Hassany, B

El Hanbali, F

Akssira, M

Mellouki, F

Haidour, A

Barrero, AF

机构：

[1] Univ Hassan II Mohammedia, Chim Bioorgan & Analyt Lab, Mohammadia, Morocco

[2] Inst Biotecnol, Dept Quim Organ, Fac Ciencias, Granada 18071, Spain

来源：

FITOTERAPIA | 2004年 / 75卷 / 06期

关键词：

Anvillea radiata; 8; alpha; 9; alpha-epoxyparthenolide; cytotoxicity; antibacterial activity;

D O I：

10.1016/j.fitote.2004.06.003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The aerial parts of Anvillea radiata yielded a new germacranolide, 8alpha,9alpha-epoxyparthenolide (3), together with two known compounds, 9alpha-hydroxyparthenolide (1) and parthenolid-9-one (2). The structures of the compounds were elucidated from IR, HRMS, H-1 and C-13-NMR, COSY, HETCOR, HMBC and HOHAHA spectral data. The major component 1 was tested for its cytotoxicity and antibacterial activity. (C) 2004 Published by Elsevier B.V.

引用

页码：573 / 576

页数：4

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