Psychotropic medicine beliefs, side effects and adherence in schizophrenia: a patient-caregiver dyad perspective

被引:2
作者
Kretchy, Irene A. [1 ]
Appiah, Bernard [2 ]
Agyabeng, Kofi [3 ]
Kwarteng, Emmanuel M. [1 ]
Ganyaglo, Enyonam [4 ]
Aboagye, Grace Owusu [5 ]
机构
[1] Univ Ghana, Coll Hlth Sci, Sch Pharm, Dept Pharm Practice & Clin Pharm, POB LG 43, Legon, Ghana
[2] Syracuse Univ, Dept Publ Hlth, Falk Coll, White Hall, Syracuse, NY 13244 USA
[3] Univ Ghana, Coll Hlth Sci, Sch Publ Hlth, Dept Biostat, POB LG13, Legon, Ghana
[4] Accra Psychiat Hosp, Dept Pharm, Accra, Ghana
[5] Korle Bu Teaching Hosp, Dept Psychiat, Accra, Ghana
关键词
Beliefs; Caregivers; Ghana; Medication adherence; Psychotropic medications; Schizophrenia; MINI-MENTAL-STATE; MEDICATION ADHERENCE; ANTIPSYCHOTIC MEDICATION; RISK-FACTORS; NONADHERENCE; DISORDERS; RELAPSE; BURDEN; QUESTIONNAIRE; RELIABILITY;
D O I
10.1007/s11096-021-01264-9
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Background Medication adherence is essential in the management of schizophrenia. Yet poor treatment uptake has negative consequences on patients and their primary caregivers. Objective To examine the association among beliefs about psychotropic medications, side effects and adherence from a patient-caregiver dyad perspective. Setting This study was conducted in a public psychiatric hospital setting in Accra, Ghana. Methods A cross-sectional study was conducted among 121 patient-caregiver dyads using an interviewer-administered data collection approach.Main outcome measure Beliefs about medicines, side-effects and medication adherence. Results The patient and caregiver-reported level of medication adherence was 28.1 %. Using the Kappa index, the level of agreement between the responses of patients and their caregivers ranged from slight to moderate. Both patients and caregivers rated necessity higher than concern (patients: 1.67 +/- 0.84, caregiver: 1.79 +/- 0.96). Significant positive relations between specific-necessity, necessity-concerns differential and medication adherence were recorded while specific-concern, general harm and side-effects correlated negatively with medication adherence from the dyad. The odds of adhering to medications increased by 58 and 64 % for each unit increase in specific-necessity and general overuse scores respectively. However, a unit increase in specific-concern score and high side-effects scores were associated with lower odds of adherence. Conclusions This study highlights the need for patient-caregiver collaborations in decision-making relating to medication adherence in schizophrenia. Thus, in clinical practice, there is the need to recognize that caregivers are essential partners, and patient-caregiver views about psychotropic medications are critical in enhancing adherence for positive mental health outcomes.
引用
收藏
页码:1370 / 1380
页数:11
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