Ewing sarcoma

被引:52
作者
Eaton, Bree R. [1 ]
Claude, Line [2 ]
Indelicato, Daniel J. [3 ]
Vatner, Ralph [4 ]
Yeh, Brian [5 ]
Schwarz, Rudolf [6 ]
Laack, Nadia [7 ]
机构
[1] Emory Univ, Radiat Oncol, Winship Canc Inst, Atlanta, GA 30322 USA
[2] Ctr Leon Berard, Radiat Oncol, Lyon, France
[3] Univ Florida, Coll Med, Radiat Oncol, Jacksonville, FL USA
[4] Univ Cincinnati, Radiat Oncol, Cincinnati, OH USA
[5] Mt Sinai Hosp, Radiat Oncol, New York, NY 10029 USA
[6] Univ Med Ctr Hamburg Eppendorf, Outpatient Ctr, Radiotherapy & Radiooncol, Hamburg, Germany
[7] Mayo Clin, Radiat Oncol, Rochester, MN USA
关键词
chemotherapy; Ewing; metastasis; radiotherapy; sarcoma; surgery;
D O I
10.1002/pbc.28355
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Ewing sarcoma is a rare tumor that requires complex multidisciplinary management. This report describes the general management and standard radiotherapy guidelines in both North America (Children's Oncology Group) and Europe (International Society of Pediatric Oncology). Standard treatment involves multiagent induction chemotherapy followed by local treatment with surgery, definitive radiation, or a combination of surgery and radiation followed by additional chemotherapy and consolidation local treatment to metastatic sites. The data supporting the role of chemotherapy, surgery, and radiation and specific radiation therapy guidelines are presented.
引用
收藏
页数:8
相关论文
共 73 条
[1]   Identification of Patients With Localized Ewing Sarcoma at Higher Risk for Local Failure: A Report From the Children's Oncology Group [J].
Ahmed, Safia K. ;
Randall, R. Lor ;
DuBois, Steven G. ;
Harmsen, William S. ;
Krailo, Mark ;
Marcus, Karen J. ;
Janeway, Katherine A. ;
Geller, David S. ;
Sorger, Joel I. ;
Womer, Richard B. ;
Granowetter, Linda ;
Grier, Holcombe E. ;
Gorlick, Richard G. ;
Laack, Nadia N. I. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2017, 99 (05) :1286-1294
[2]  
Ahrens S, 1999, MED PEDIATR ONCOL, V32, P186, DOI 10.1002/(SICI)1096-911X(199903)32:3<186::AID-MPO5>3.0.CO
[3]  
2-D
[4]   EWING SARCOMA - LOCAL TUMOR-CONTROL AND PATTERNS OF FAILURE FOLLOWING LIMITED-VOLUME RADIATION-THERAPY [J].
ARAI, Y ;
KUN, LE ;
BROOKS, MT ;
FAIRCLOUGH, DL ;
FONTANESI, J ;
MEYER, WH ;
HAYES, FA ;
THOMPSON, E ;
RAO, BN .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1991, 21 (06) :1501-1508
[5]   Prognostic factors in non-metastatic Ewing's sarcoma tumor of bone: An analysis of 579 patients treated at a single institution with adjuvant or neoadjuvant chemotherapy between 1972 and 1998 [J].
Bacci, Gaetano ;
Longhi, Alessandra ;
Ferrari, Stefano ;
Mercuri, Mario ;
Versari, Michela ;
Bertoni, Franco .
ACTA ONCOLOGICA, 2006, 45 (04) :469-475
[6]   Improved survival using specialized multidisciplinary board in sarcoma patients [J].
Blay, J-Y ;
Soibinet, P. ;
Penel, N. ;
Bompas, E. ;
Duffaud, F. ;
Stoeckle, E. ;
Mir, O. ;
Adam, J. ;
Chevreau, C. ;
Bonvalot, S. ;
Rios, M. ;
Kerbrat, P. ;
Cupissol, D. ;
Anract, P. ;
Gouin, F. ;
Kurtz, J-E ;
Lebbe, C. ;
Isambert, N. ;
Bertucci, F. ;
Toumonde, M. ;
Thyss, A. ;
Piperno-Neumann, S. ;
Dubray-Longeras, P. ;
Meeus, P. ;
Ducimetiere, F. ;
Giraud, A. ;
Coindre, J-M ;
Ray-Coquard, I. ;
Italiano, A. ;
Le Cesne, A. .
ANNALS OF ONCOLOGY, 2017, 28 (11) :2852-2859
[7]  
Bölling T, 2008, STRAHLENTHER ONKOL, V184, P193, DOI 10.1007/s00066-008-1810-x
[8]   Radiation Toxicity Following Busulfan/Melphalan High-dose Chemotherapy in the EURO-EWING-99-trial: Review of GPOH Data [J].
Boelling, Tobias ;
Dirksen, Uta ;
Ranft, Andreas ;
Ernst, Iris ;
Juergens, Heribert ;
Willich, Normann .
STRAHLENTHERAPIE UND ONKOLOGIE, 2009, 185 :21-22
[9]  
Brennan B, 2020, J CLIN ONCOL, V38
[10]  
Brown Lindsay C., 2014, Sarcoma, V2014, P418270, DOI 10.1155/2014/418270