INFLUENCE OF SEXUAL HORMONES ON OXYGEN CONSUMPTION IN RATS

被引:1
作者
Conti, Filipe Fernandes [1 ]
Sanches, Iris Callado [1 ]
Bernardes, Nathalia [1 ,2 ]
Shimojo, Guilherme Lemos [1 ]
Taboas Figueroa, Diego Mendrot [2 ]
Wichi, Rogerio Brandao [3 ]
De Angelis, Katia [1 ]
机构
[1] Univ Nove Julho, Lab Fisiol Translac, Sao Paulo, Brazil
[2] Inst Coracao FMUSP, Lab Hipertensao Expt, Sao Paulo, Brazil
[3] Univ Fed Sergipe, Sao Cristovao, SE, Brazil
关键词
oxygen consumption; rats; sex differences; menopause; MENSTRUAL-CYCLE; RISK-FACTORS; VO2MAX; DISEASE;
D O I
10.1590/1517-86922014200601665
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Introduction: Literature findings suggest that fluctuations of female sex hormones may change the maximum oxygen consumption (VO2max). Objective: To compare the VO2max among male rats (M, n = 8), female rats on ovulatory (OV, n= 8) or non- ovulatory (NOV, n= 8) phases of the estrous cycle and ovariectomized (OS, n= 8). Methods: The evaluation of oxygen consumption was performed on a treadmill coupled with metabolic box. Results: At rest VO2 was similar among groups. The M group had a higher VO2 max compared to the NOV group, however showed similar values when compared to OV group. The VO2 max was lower in the ovariectomized group (OS: 62 +/- 3 ml.kg(-1).min(-1)) compared to other groups (M:92 +/- 2; NOV: 77 +/- 4; OV: 87 +/- 3 ml.kg(-1).min(-1)). Conclusions: These findings suggest that hormonal variation resulting from different phases of the estrous cycle and ovarian hormone deprivation can induce changes in maximal oxygen uptake in rats.
引用
收藏
页码:421 / 423
页数:3
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