Crocin and geniposide profiles and radical scavenging activity of gardenia fruits (Gardenia jasminoides Ellis) from different cultivars and at the various stages of maturation

被引:52
作者
Chen, Yang [1 ,2 ]
Zhang, Hao [1 ]
Li, Yi-Xin [3 ]
Cai, Le [4 ]
Huang, Juan [1 ]
Zhao, Can [2 ]
Jia, Lin [2 ]
Buchanan, Ryan [2 ]
Yang, Ting [2 ]
Jiang, Li-Juan [2 ]
机构
[1] Sichuan Univ, W China Sch Pharm, Chengdu 610041, Peoples R China
[2] Zunyi Med Coll, Dept Chem, Zhuhai 519041, Guangdong, Peoples R China
[3] Xili Hosp, Shenzhen 518055, Peoples R China
[4] Yunnan Univ, Sch Chem Sci & Technol, Minist Educ, Key Lab Med Chem Nat Resource, Kunming 650091, Peoples R China
关键词
Gardenia; Geniposide; Crocin; DPPH; Cultivar; Maturation; CROCETIN DERIVATIVES; SATIVUS; ESTERS; CELLS;
D O I
10.1016/j.fitote.2009.09.011
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The major components of gardenia fruits are geniposide and water soluble pigment crocins. In this study, we investigate crocins and geniposide profiles of gardenia fruits from different cultivars and at the various stages of maturation. DPPH scavenging activity of gardenia fruits from different cultivars and at the various stages of fruit maturation was also assayed. Quantitative determination of crocins in the gardenia at the various stages of maturation revealed a significant increase when ripening. However, geniposide content was negatively correlated with ripening stages. A significant difference was observed when comparing crocin content of different gardenia from various cultivars and geniposide content also showed marked variety. Current study indicated no relationship between crocin and geniposide content in gardenia fruits at the various stages of maturation and DPPH radical scavenging activity. Data showed that, although crocins feature markedly less DPPH scavenging activity than gardenia ethanol extract, total crocin content of gardenias collected in various cultivars correlate, to a certain degree, with radical scavenging effects of the Chinese traditional medicine (r=0.75). (C) 2009 Published by Elsevier B.V.
引用
收藏
页码:269 / 273
页数:5
相关论文
共 13 条
[1]   Neuroprotection by crocetin in a hemi-parkinsonian rat model [J].
Ahmad, AS ;
Ansari, MA ;
Ahmad, M ;
Saleem, S ;
Yousuf, S ;
Hoda, MN ;
Islam, F .
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2005, 81 (04) :805-813
[2]   Crocetin esters, picrocrocin and its related compounds present in Crocus sativus stigmas and Gardenia jasminoides fruits.: Tentative identification of seven new compounds by LC-ESI-MS [J].
Carmona, M ;
Zalacain, A ;
Sánchez, AM ;
Novella, JL ;
Alonso, GL .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2006, 54 (03) :973-979
[3]   Isolation and characterization of the major colorant in Gardenia fruit [J].
Choi, HJ ;
Park, YS ;
Kim, MG ;
Kim, TK ;
Yoon, NS ;
Lim, YJ .
DYES AND PIGMENTS, 2001, 49 (01) :15-20
[4]   Effect of crocin on experimental atherosclerosis in quails and its mechanisms [J].
He, SY ;
Qian, ZY ;
Tang, FT ;
Wen, N ;
Xu, GL ;
Sheng, L .
LIFE SCIENCES, 2005, 77 (08) :907-921
[5]  
ICHI T, 1995, J JPN SOC FOOD SCI, V42, P776
[6]   Antihyperlipidemic effect of crocin isolated from the fructus of Gardenia jasminoides and its metabolite crocetin [J].
Lee, IA ;
Lee, JH ;
Baek, NI ;
Kim, DH .
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2005, 28 (11) :2106-2110
[7]   An investigation of antioxidant capacity of fruits in Singapore markets [J].
Leong, LP ;
Shui, G .
FOOD CHEMISTRY, 2002, 76 (01) :69-75
[8]   Crocin prevents the death of rat pheochromyctoma (PC-12) cells by its antioxidant effects stronger than those of α-tocopherol [J].
Ochiai, T ;
Ohno, S ;
Soeda, S ;
Tanaka, H ;
Shoyama, Y ;
Shimeno, H .
NEUROSCIENCE LETTERS, 2004, 362 (01) :61-64
[9]   Isolation and structure elucidation of carotenoid-glycosyl esters in gardenia fruits (Gardenia jasminoides Ellis) and saffron (Crocus sativus Linne) [J].
Pfister, S ;
Meyer, P ;
Steck, A ;
Pfander, H .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1996, 44 (09) :2612-2615
[10]   CROCETIN PROTECTS AGAINST OXIDATIVE DAMAGE IN RAT PRIMARY HEPATOCYTES [J].
TSENG, TH ;
CHU, CY ;
HUANG, JM ;
SHIOW, SJ ;
WANG, CJ .
CANCER LETTERS, 1995, 97 (01) :61-67