An Estimate of Cancers Attributable to Occupational Exposures in France

被引：57

作者：

Boffetta, Paolo ^{[1
,2
]}

Autier, Philippe ^{[1
]}

Boniol, Mathieu ^{[1
]}

Boyle, Peter ^{[1
]}

Hill, Catherine ^{[3
,4
]}

Aurengo, Andre ^{[5
,6
,10
]}

Masse, Roland ^{[10
,11
]}

de The, Guy ^{[7
,10
]}

Valleron, Alain-Jacques ^{[5
,8
,9
,11
]}

Monier, Roger ^{[3
]}

Tubiana, Maurice ^{[3
,11
]}

机构：

[1] Int Prevent Res Inst, F-69006 Lyon, France

[2] Mt Sinai Sch Med, Tisch Canc Inst, New York, NY USA

[3] Inst Gustave Roussy, Villejuif, France

[4] Federat Natl Ctr Lutte Canc, Paris, France

[5] Univ Paris 06, Paris, France

[6] Hop La Pitie Salpetriere, Paris, France

[7] Inst Pasteur, Paris, France

[8] INSERM, UMR S 707, Paris, France

[9] Hop St Antoine, F-75571 Paris, France

[10] Med Acad, Paris, France

[11] Inst France, Acad Sci, Paris, France

来源：

JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE | 2010年 / 52卷 / 04期

关键词：

LUNG-CANCER; RISK; MORTALITY; COHORTS; MESOTHELIOMA; CARCINOGENS; PROPORTION; RADIATION; WORKERS; BURDEN;

D O I：

10.1097/JOM.0b013e3181d5e355

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objective: To perform a quantitative estimate of the proportion of cancers attributable to occupational exposures in France in 2000. Methods: Exposure data for established carcinogens were obtained from a 1994 survey and other sources. Relative risks for 23 exposure-cancer combinations were derived from meta-analyses and pooled analyses. Results: A total of 4335 cases of cancer among men (2.7% of all cancers) and 403 cases among women (0.3% of all cancers) were attributed to occupational exposures. Asbestos, polycyclic aromatic hydrocarbons, and chromium VI were the main occupational carcinogens in men, and asbestos and involuntary smoking were the main carcinogens in women. Corresponding proportions for cancer deaths were 4.0% and 0.6% in men and women, respectively. Lung cancer represented 75% of deaths attributable to occupational exposures. Conclusion: Our estimates are comparable with those obtained for other countries in studies based on similar methodology.

引用

页码：399 / 406

页数：8

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