A Novel Poly(vinylidene fluoride)-Based 4-Miktoarm Star Terpolymer: Synthesis and Self-Assembly

被引：20
作者：
Patil, Yogesh
Bilalis, Panayiotis
Polymeropoulos, George
Almahdali, Sarah
Hadjichristidis, Nikos
Rodionov, Valentin [1 ]
机构：
[1] KAUST, KAUST Catalysis Ctr, Thuwal 239556900, Saudi Arabia
来源：
MOLECULAR PHARMACEUTICS | 2018年 / 15卷 / 08期
关键词：
poly(vinylidene fluoride); miktoarm star polymer; iodine transfer polymerization; CuAAC; self-assembly; NILE RED; BLOCK; PVDF; COPOLYMERS; POLYMERIZATION; MEMBRANES; POLYMERS; MESHES;
D O I：
10.1021/acs.molpharmaceut.8b00010
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
A well-defined amphiphilic miktoarm polymer incorporating poly-(vinylidene fluoride) (PVDF), polystyrene (PS), and poly(ethylene glycol) (PEG) blocks was synthesized via a combination of atom-transfer radical polymerization (ATRP), iodine transfer radical polymerization (ITP), and copper-catalyzed azide-alkyne cyclo-addition (CuAAC). Morphology and self-assembly of this star polymer were examined in organic solvents and in water. The aggregates formed in water were found to possess unusual frustrated topology due to immiscibility of PS and PVDF. The polymer was evaluated for transport of small hydrophobic molecules in water.
引用
收藏
页码：3005 / 3009
页数：5
相关论文
共 30 条
  • [21] Fluorous micro- and nanophases with a biomedical perspective
    Riess, JG
    [J]. TETRAHEDRON, 2002, 58 (20) : 4113 - 4131
  • [22] Mechanism of the ligand-free CuI-catalyzed azide-alkyne cycloaddition reaction
    Rodionov, VO
    Fokin, VV
    Finn, MG
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (15) : 2210 - 2215
  • [23] Rostovtsev VV, 2002, ANGEW CHEM INT EDIT, V41, P2596, DOI 10.1002/1521-3773(20020715)41:14<2596::AID-ANIE2596>3.0.CO
  • [24] 2-4
  • [25] Poly(vinylidene fluoride-trifluoroethylene)/NAY zeolite hybrid membranes as a drug release platform applied to ibuprofen release
    Salazar, H.
    Lima, A. C.
    Lopes, A. C.
    Botelho, G.
    Lanceros-Mendez, S.
    [J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2015, 469 : 93 - 99
  • [26] Seidner L., 1993, US, Patent No. [5244981, 005244981A, 005244981]
  • [27] Reconstruction of a quadriceps tendon tear using Polyvinylidene fluoride sutures and patellar screw fixation: A biomechanical study
    Sellei, R. M.
    Bauer, E.
    Hofman, M.
    Kobbe, P.
    Lichte, P.
    Garrison, R. L.
    Pape, H. C.
    Horst, K.
    [J]. KNEE, 2015, 22 (06) : 535 - 541
  • [28] Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(I)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides
    Tornoe, CW
    Christensen, C
    Meldal, M
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2002, 67 (09) : 3057 - 3064
  • [29] Well-Defined Copolymers Based on Poly(vinylidene fluoride): From Preparation and Phase Separation to Application
    Voet, Vincent S. D.
    ten Brinke, Gerrit
    Loos, Katja
    [J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2014, 52 (20) : 2861 - 2877
  • [30] Block copolymer route towards poly(vinylidene fluoride)/poly(methacrylic acid)/nickel nanocomposites
    Voet, Vincent S. D.
    Hermida-Merino, Daniel
    ten Brinke, Gerrit
    Loos, Katja
    [J]. RSC ADVANCES, 2013, 3 (21) : 7938 - 7946
123