Wideband radio-frequency device for measurements of dielectric properties of small volumes of liquids

被引：8

作者：

Kozhevnikov, Alexay ^{[1
]}

机构：

[1] Penn State Univ, Dept Phys, University Pk, PA 16802 USA

来源：

MEASUREMENT SCIENCE AND TECHNOLOGY | 2010年 / 21卷 / 04期

关键词：

dielectric spectroscopy; complex dielectric function; wideband microwave measurements; radio-frequency spectroscopy; SPECTROSCOPY;

D O I：

10.1088/0957-0233/21/4/043001

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

A wideband differential detector for high-sensitivity rf and microwave dielectric spectroscopy of liquids is described. The device is unique in that it has very high wideband sensitivity and requires extremely small (nanoliter range) volumes of the liquid. In addition, the device has good linearity and can be used for quantitative extraction of the frequency-dependent dielectric function epsilon(omega) of extremely small volumes of liquids. Using this device, quantitative measurements of the dielectric function at frequencies from 50 MHz to 1.6 GHz are demonstrated for 200 nL volume samples of liquids. The detector may be used for wideband rf/microwave spectroscopic analysis of chemical and biological samples.

引用

页数：5

共 19 条

[1] DIELECTRIC MEASUREMENTS USING A RATIONAL-FUNCTION MODEL [J].

ANDERSON, JM ;

SIBBALD, CL ;

STUCHLY, SS .

IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, 1994, 42 (02) :199-204

[2] Characterization of biological cells by dielectric spectroscopy [J].

Asami, K .

JOURNAL OF NON-CRYSTALLINE SOLIDS, 2002, 305 (1-3) :268-277

[3] Microwave dielectric characterization of binary mixtures of water, methanol, and ethanol [J].

Bao, JZ ;

Swicord, ML ;

Davis, CC .

JOURNAL OF CHEMICAL PHYSICS, 1996, 104 (12) :4441-4450

[4] Cellular dielectric spectroscopy: A powerful new approach to label-free cellular analysis [J].

Ciambrone, GJ ;

Liu, VF ;

Lin, DC ;

McGuinness, RP ;

Leung, GK ;

Pitchford, S .

JOURNAL OF BIOMOLECULAR SCREENING, 2004, 9 (06) :467-480

[5] Dielectric spectroscopy for bioanalysis: From 40 Hz to 26.5 GHz in a microfabricated wave guide [J].

Facer, GR ;

Notterman, DA ;

Sohn, LL .

APPLIED PHYSICS LETTERS, 2001, 78 (07) :996-998

[6] Monitoring of density changes in low-permittivity liquids by microwave-permittivity measurements with an open-ended probe [J].

Friiso, T ;

Tjomsland, T .

MEASUREMENT SCIENCE AND TECHNOLOGY, 1997, 8 (11) :1295-1305

[7]

Grant E.H., 1978, Dielectric Behaviour of Biological Molecules in Solution

[8] A review of RF and microwave techniques for dielectric measurements on polar liquids [J].

Gregory, Andrew P. ;

Clarke, Robert N. .

IEEE TRANSACTIONS ON DIELECTRICS AND ELECTRICAL INSULATION, 2006, 13 (04) :727-743

[9] Sensitive detection method of dielectric dispersions in aqueous-based, surface-bound macromolecular structures using microwave spectroscopy [J].

Hefti, J ;

Pan, A ;

Kumar, A .

APPLIED PHYSICS LETTERS, 1999, 75 (12) :1802-1804

[10]

JEAN BR, 2008, SAS 2008 IEEE SENS A

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