Tuberculosis course in patients with HIV-infection

Aim. To evaluate clinical features of tuberculosis in correlation with HIV-infection duration. Material and methods. 117 patients with HIV-infection were divided into three groups: HIV-infected in the presence of long-standing tuberculosis (group 1), HIV- and tuberculosis-infected simultaneously (group 2), tuberculosis-infected 5-10 years after getting HIV-infection. Conclusion. Clinical picture and course of tuberculous infection in HIV-infected patients depend on the time of getting HIV-infection and are determined by the severity of T-cell immunodeficiency. Results. Tuberculosis runs its usual course in patients of groups 1 and 2. In group 3 tuberculosis ran atypically, had lethal outcome due to either tuberculosis or opportunistic infections.