Total synthesis of analogs of topostin B, a DNA topoisomerase I inhibitor. Part 3. Improved synthesis of topostin B-1 analogs

被引：2

作者：

Fujiwara, H ^{[1
]}

Aoyama, T ^{[1
]}

Shioiri, T ^{[1
]}

机构：

[1] Nagoya City Univ, Fac Pharmaceut Sci, Mizuho Ku, Nagoya, Aichi 467, Japan

来源：

TETRAHEDRON | 1998年 / 54卷 / 3-4期

关键词：

D O I：

10.1016/S0040-4020(97)10315-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Analogs or (E)-topostin B-1 (1a-c) and (Z)-topostin B-1 (2a-c), an inhibitor of mammalian DNA topoisomerase I, have been synthesized in a convenient manner. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：551 / 564

页数：14

共 10 条

[1] PREPARATION AND USE OF TETRA-NORMAL-BUTYLAMMONIUM PER-RUTHENATE (TBAP REAGENT) AND TETRA-NORMAL-PROPYLAMMONIUM PER-RUTHENATE (TPAP REAGENT) AS NEW CATALYTIC OXIDANTS FOR ALCOHOLS
GRIFFITH, WP
LEY, SV
WHITCOMBE, GP
WHITE, AD
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1987, (21) : 1625 - 1627
[2] STEREOCONTROL IN HORNER-WADSWORTH-EMMONS CONDENSATIONS OF A GEM-DIMETHYLCYCLOPROPYL ALDEHYDE WITH ALPHA-SUBSTITUTED PHOSPHONO ACETATES
HAMMOND, GB
COX, MB
WIEMER, DF
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (01) : 128 - 132
[3] TOPOSTIN, A NOVEL INHIBITOR OF MAMMALIAN DNA TOPOISOMERASE-I FROM FLEXIBACTER-TOPOSTINUS SP-NOV .2. PURIFICATION AND SOME PROPERTIES OF TOPOSTIN
IKEGAMI, Y
TAKEUCHI, N
HANADA, M
HASEGAWA, Y
ISHII, K
ANDOH, T
SATO, T
SUZUKI, K
YAMAGUCHI, H
MIYAZAKI, S
NAGAI, K
WATANABE, S
SAITO, T
[J]. JOURNAL OF ANTIBIOTICS, 1990, 43 (02) : 158 - 162
[4] A CONVENIENT PROCEDURE FOR THE MONOSILYLATION OF SYMMETRICAL 1,N-DIOLS
MCDOUGAL, PG
RICO, JG
OH, YI
CONDON, BD
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (17) : 3388 - 3390
[5] TOTAL SYNTHESIS OF ANALOGS OF TOPOSTIN-B, A DNA TOPOISOMERASE-I INHIBITOR .1. SYNTHESIS OF FRAGMENTS OF TOPOSTIN-B-1 ANALOGS
NOGUCHI, H
AOYAMA, T
SHIOIRI, T
[J]. TETRAHEDRON, 1995, 51 (38) : 10531 - 10544
[6] TOTAL SYNTHESIS OF ANALOGS OF TOPOSTIN-B, A DNA TOPOISOMERASE-I INHIBITOR .2. SYNTHESIS OF TOPOSTIN-B-1 ANALOGS
NOGUCHI, H
AOYAMA, T
SHIOIRI, T
[J]. TETRAHEDRON, 1995, 51 (38) : 10545 - 10560
[7] TOTAL SYNTHESIS OF (+/-)-DELTA-9(12)-CAPNELLENE-8-BETA,10-ALPHA-DIOL
PATTENDEN, G
TEAGUE, SJ
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1988, (05): : 1077 - 1083
[8] Vitamin E. XLI. Synthesis of 1-chloro-3,7,11,15-tetramethylhexadecanol-3, and its condensation with trimethylhydroquinone to form alpha-tocopherol
Smith, LI
Sprung, JA
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1943, 65 : 1276 - 1283
[9] TOPOSTIN, A NOVEL INHIBITOR OF MAMMALIAN DNA TOPOISOMERASE-I FROM FLEXIBACTER-TOPOSTINUS SP-NOV .1. TAXONOMY, AND FERMENTATION OF PRODUCING STRAIN
SUZUKI, K
YAMAGUCHI, H
MIYAZAKI, S
NAGAI, K
WATANABE, S
SAITO, T
ISHII, K
HANADA, M
SEKINE, T
IKEGAMI, Y
ANDOH, T
[J]. JOURNAL OF ANTIBIOTICS, 1990, 43 (02) : 154 - 157
[10] TOTAL SYNTHESIS OF (+)-DESEPOXYASPERDIOL
TIUS, MA
FAUQ, AH
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (05) : 1035 - 1039

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