Declining incidence of dementia: A national registry-based study over 20 years

被引:35
作者
Taudorf, Laerke [1 ]
Norgaard, Ane [1 ]
Islamoska, Sabrina [2 ]
Jorgensen, Kasper [1 ]
Laursen, Thomas Munk [3 ]
Waldemar, Gunhild [1 ]
机构
[1] Univ Copenhagen, Dept Neurol, Rigshosp, Danish Dementia Res Ctr, Copenhagen O, Denmark
[2] Univ Copenhagen, Dept Publ Hlth, Copenhagen K, Denmark
[3] Aarhus Univ, Aarhus BSS, Dept Econ & Business Econ, Natl Ctr Register Based Res, Aarhus, Denmark
关键词
Dementia; Incidence; Prevalence; Time trend; Epidemiology; Registry study; Nationwide study; COGNITIVE FUNCTION; AFRICAN-AMERICANS; PREVALENCE; TRENDS; POPULATION; COHORT;
D O I
10.1016/j.jalz.2019.07.006
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction: The aim of this study was to investigate the registry-based national time trends in incidence and prevalence rates of dementia from 1996 to 2015. Methods: We assessed annual incidence and prevalence using longitudinal data from nationwide registries on dementia status and demographics on all residents >= 65 years old in Denmark. Results: Our population comprised 2 million people, of whom 152,761 were diagnosed with dementia. The age- and sex-adjusted incidence rate increased, on average, by 9% annually from 1996 to 2003, followed by a 2% annual decline, while total prevalence increased during the whole period. Discussion: This is the first study to report continuous time trends of incidence and prevalence in an entire national population. The incidence rate has declined steadily since 2003, while the total prevalence is still increasing. Future health care planning on prevention and treatment of dementia should take these findings into account. (C) 2019 The Authors. Published by Elsevier Inc.
引用
收藏
页码:1383 / 1391
页数:9
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