Bioanalytical applications of 'fast chromatography' to high-throughput liquid chromatography/tandem mass spectrometric quantitation

被引：0
|
作者：
Romanyshyn, L [1 ]
Tiller, PR [1 ]
Hop, CECA [1 ]
机构：
[1] Merck Res Labs, Drug Metab, Rahway, NJ 07065 USA
来源：
RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 2000年 / 14卷 / 18期
关键词：
D O I：
10.1002/1097-0231(20000930)14:18<1662::AID-RCM77>3.3.CO;2-E
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A fast chromatographic separation approach that enables rapid method development for high-throughput sample quantification is discussed. This approach has been used to analyze samples from various biological matrices. Data are presented from in vivo pharmaokinetic studies (plasma) and in vitro drug metabolism and transport studies (hepatic microsomes, hepatocytes, and Caco-2 cells). Copyright (C) 2000 John Wiley & Sons, Ltd.
引用
收藏
页码：1662 / 1668
页数：7
相关论文
共 50 条
  • [1] Bioanalytical applications of 'fast chromatography' to high-throughput liquid chromatography/tandem mass spectrometric quantitation
    Romanyshyn, L., 1662, John Wiley and Sons Ltd (14)
  • [2] High-throughput liquid chromatography-tandem mass spectrometric analysis of sirolimus in whole blood
    Wallemacq, PE
    Vanbinst, R
    Asta, S
    Cooper, DP
    CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2003, 41 (07) : 921 - 925
  • [3] High-throughput chiral liquid chromatography/tandem mass spectrometry
    Bakhtiar, R
    Tse, FLS
    RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2000, 14 (13) : 1128 - 1135
  • [4] A flexible and high throughput liquid chromatography-tandem mass spectrometric assay for the quantitation of telcagepant in human plasma
    Du, Lihong
    Miller-Stein, Cynthia M.
    Valesky, Robert J.
    Martucci, Ashley N.
    Woolf, Eric J.
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2009, 877 (14-15): : 1465 - 1471
  • [5] Column switching in high-performance liquid chromatography with tandem mass spectrometric detection for high-throughput preclinical pharmacokinetic studies
    Gao, VCX
    Luo, WC
    Ye, QP
    Thoolen, M
    JOURNAL OF CHROMATOGRAPHY A, 1998, 828 (1-2) : 141 - 148
  • [6] High-Throughput Quantitation of Cannabinoids by Liquid Chromatography Triple-Quadrupole Mass Spectrometry
    Tran, Jonathan
    Elkins, Aaron C.
    Spangenberg, German C.
    Rochfort, Simone J.
    MOLECULES, 2022, 27 (03):
  • [7] Quantitation of glycation adducts in HDL by liquid chromatography with tandem mass spectrometric detection
    Rabbani, N.
    Thornalley, P. J.
    ATHEROSCLEROSIS SUPPLEMENTS, 2007, 8 (01) : 35 - 35
  • [8] Fast liquid chromatography for high-throughput screening of polymers
    Pasch, H
    Kilz, P
    MACROMOLECULAR RAPID COMMUNICATIONS, 2003, 24 (01) : 104 - 108
  • [9] Automated high-throughput assay for microsomal binding with ultra fast liquid chromatography-tandem mass spectrometry
    Lau, Yau Yi
    Doktor, Stella
    de Morais, Sonia M.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [10] High-throughput plasma docetaxel quantification by liquid chromatography-tandem mass spectrometry
    Corona, Giuseppe
    Elia, Caterina
    Casetta, Bruno
    Frustaci, Sergio
    Toffoli, Giuseppe
    CLINICA CHIMICA ACTA, 2011, 412 (3-4) : 358 - 364
12345