p-nitrobenzoic acid promoted synthesis of 1,5-benzodiazepine derivatives

被引：0

作者：

Varala, Ravi ^{[1
]}

Enugala, Ramu ^{[1
]}

Adapa, Srinivas R. ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2007年 / 18卷 / 02期

关键词：

1,5-benzodiazepines; bronsted acid; o-phenylenediamines and ketones; p-nitrobenzoic acid;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

p-Nitrobenzoic acid was found to be the versatile Bronsted organic acid promoter among the carboxylic acids tested for the preparation of 1,5-benzodiazepine derivatives from a wide range of substituted o-phenylenediamines and ketones. The corresponding products were obtained in good isolated yields (62-92%) under mild conditions using acetonitrile as solvent at ambient temperature. Further, the reagent could be easily recovered and reused.

引用

页码：291 / 296

页数：6