HIV-associated Hodgkin's disease

被引：17

作者：

Powles, T ^{[1
]}

Bower, M ^{[1
]}

机构：

[1] Chelsea & Westminster Hosp, Dept Oncol, London SW10 9NH, England

来源：

INTERNATIONAL JOURNAL OF STD & AIDS | 2000年 / 11卷 / 08期

关键词：

HIV; AIDS; Hodgkin's disease; lymphoma;

D O I：

10.1258/0956462001916362

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Hodgkin's disease (HD) appears to occur more frequently in people with HIV and within this population HD demonstrates a number of differences. In people with HIV, Epstein-Barr virus (EBV) is found more frequently in Reed-Sternberg cells and mixed cellularity and lymphocyte depleted histological subtypes predominate. Patients with HIV present with more advanced stage HD of ten with extranodal disease. The prognostic variables for HD in patients with HIV relate to the HIV rather than the HD. In people with HIV the response rates are lower, the relapse rates higher, the infectious complications more frequent and the overall survival worse than for HD in the general population.

引用

页码：492 / 494

页数：3

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