Recent Advances in the Catalytic Enantioselective Reactions of para-Quinone Methides

被引:196
作者
Li, Wenjun [1 ]
Xu, Xianhong [1 ]
Zhang, Pengfei [2 ]
Li, Pengfei [2 ]
机构
[1] Qingdao Univ, Dept Med Chem, Sch Pharm, 38 Dengzhou Rd, Qingdao 266021, Shandong, Peoples R China
[2] Southern Univ Sci & Technol, Dept Chem, 1088 Xueyuan Blvd, Shenzhen 518055, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
annulation; asymmetric catalysis; conjugate addition; para-quinone methides; synthetic methods; ASYMMETRIC 1,6-CONJUGATE ADDITION; BETA; BETA-DIARYL-ALPHA-AMINO ACID-ESTERS; RAUHUT-CURRIER REACTION; STEREOGENIC CENTERS; OXINDOLES; ADDITION/AROMATIZATION; DIHYDROCOUMARINS; POLYMERIZATIONS; 1,6-ADDITION; ALKYLATION;
D O I
10.1002/asia.201800415
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In recent years, the catalytic enantioselective reactions of p-QMs have drawn much attention, because of their distinctive reactivities. As such, a variety of chiral catalytic systems have been developed. This Focus Review describes the reactions of p-QMs according to the chiral catalyst system used, with the aim of provide the first complete picture of the exciting developments in this field. Special emphasis is placed on recent work regarding their reaction mechanisms.
引用
收藏
页码:2350 / 2359
页数:10
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