Synthesis of new estrone derivatives using excess oxalyl chloride

被引：5
作者：
Nahar, L
Sarker, SD
Li, PK
Turner, AB
机构：
[1] Univ Aberdeen, Dept Chem, Japp Lab, Aberdeen AB24, Scotland
[2] Robert Gordon Univ, Phytopharmaceut Res Lab, Sch Pharm, Aberdeen AB10 1FR, Scotland
[3] Ohio State Univ, Coll Pharm, Div Med Chem & Pharmacognosy, Columbus, OH 43210 USA
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2004年 / 40卷 / 01期
基金：
英国工程与自然科学研究理事会;
关键词：
steroids; estrone; esterification; oxalyl chloride; NMR;
D O I：
10.1023/B:CONC.0000025465.76505.33
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The synthesis and structure elucidation of three new estrone derivatives chloro-oxo-acetic acid (estra-1,3,5(10)-trien-17-on-3-yl methyl) ester (2), oxalic acid mono (estra-1,3,5(10)-trien-17-on-3-yl methyl) ester (3), and ethyl (3-methoxyestra-1,3,5(10)-trien)-17beta-yl oxalate (5) have been described.
引用
收藏
页码：50 / 53
页数：4
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