Molecular docking analysis of stevioside with Akt and PPARγ

被引：3

作者：

Deenadayalan, Abilasha ^{[1
,2
]}

Vijayalakshmi, S. ^{[1
]}

Janaki, C. S. ^{[3
]}

Jayaraman, Selvaraj ^{[4
]}

机构：

[1] Saveetha Inst Med & Tech Sci, Saveetha Med Coll & Hosp, Dept Anat, Chennai 602105, Tamil Nadu, India

[2] Asan Mem Dent Coll & Hosp, Dept Anat, Chennai 602105, Tamil Nadu, India

[3] Bharath Med Coll & Hosp, Dept Anat, Chennai 600073, Tamil Nadu, India

[4] Saveetha Univ, Saveetha Inst Med & Tech Sci, Saveetha Dent Coll & Hosp, Dept Biochem, Chennai 600077, Tamil Nadu, India

来源：

BIOINFORMATION | 2021年 / 17卷 / 01期

关键词：

Diabetes; AKT & PPAR gamma; stevioside; molecular docking; STEVIA-REBAUDIANA BERTONI;

D O I：

10.6026/97320630017283

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Stevioside is a diterpenoid glycoside consisting of an aglycone (steviol) and three glucose molecules. It is commonly used as an anti-hyperglycemic food because of its non-caloric property. Therefore, it is of interest to document the interactions of stevioside with AKT & PPAR-gamma proteins using Autodock Vina PyRx docking techniques. Results of the docking studies indicate that stevioside had more than two hydrogen bond interactions with the AKT and PPAR gamma protein for further consideration.

引用

页码：283 / 288

页数：6

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