A domino copper-catalyzed C-N and C-O cross-coupling for the conversion of primary amides into benzoxazoles

被引：182

作者：

Altenhoff, G ^{[1
]}

Glorius, F ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2004年 / 346卷 / 13-15期

关键词：

benzoxazoles; C-N and C-O cross-coupling; copper; cyclization; domino reactions; heterocycles;

D O I：

10.1002/adsc.200404182

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Benzoxazoles can be efficiently prepared in a single step and in good yield from primary amides and o-dihalobenzenes using Cu catalysis. Starting from substituted o-bromochlorobenzenes this unusual domino reaction allows the regioselective formation of benzoxazoles.

引用

页码：1661 / 1664

页数：4

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