An improved practical Pd/C-catalyzed Sonogashira cross-coupling reaction for the synthesis of liquid crystals of trans-cyclohexyltolans

被引：12
|
作者：
Shang, Hongyong [2 ]
Hua, Ruimao [1 ]
Zheng, Qingwei
Zhang, Jianli [2 ]
Liang, Xiao [2 ]
Zhu, Qiming [2 ]
机构：
[1] Tsinghua Univ, Dept Chem, Tinghua Univ, Beijing 100084, Peoples R China
[2] Shijiazhuang Developed Zone Yongsheng Huatsing Cr, Shijiazhuang 050091, Peoples R China
来源：
APPLIED ORGANOMETALLIC CHEMISTRY | 2010年 / 24卷 / 06期
关键词：
Pd/C; cuprous iodide; cross-coupling reaction; cyclohexyltolans; liquid crystals; ARYL HALIDES; PALLADIUM; ACETYLENES; CHARCOAL; CARBON;
D O I：
10.1002/aoc.1642
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
An improved practical synthesis of liquid crystals of trans-cyclohexyltolans by Sonogashira cross-coupling reaction of 1-iodo-4-(trans-4-alkylcyclohexyl)benzene with aromatic terminal alkynes in the presence of Pd/C (palladium on activated carbon) as low as 0.03 mol% of Pd and Cul (2 mol%) in a mixture solvent of acetone-water (5:2 in volume) is described. The liquid crystals could be obtained in high yields as a solid with excellent purity by simple filtration, and the filtrate could be reused several times while still retaining high catalytic activity. Copyright (C) 2010 John Wiley & Sons, Ltd.
引用
收藏
页码：473 / 476
页数：4
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