Overcoming drug resistance in lung cancer

被引：0
|
作者：
Saijo, N
Nishio, K
机构：
[1] Natl Canc Ctr, Res Inst, Div Pharmacol, Chuo Ku, Tokyo 104, Japan
[2] Natl Canc Ctr Hosp, Div Pharmacol, Natl Canc Ctr, Res Inst,Med Oncol Div, Tokyo, Japan
来源：
ONCOLOGY-NEW YORK | 1998年 / 12卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Anticancer drugs have been explored by means of random screening and demonstrated to be active against not only hematologic malignancies but also same solid tumors. Recent progress in the field of molecular biology has identified many new molecular targets for anticancer drugs. In this review, for example, signal-transduction pathways, which are influenced by newer agents like the taxanes (paclitaxel [Taxol] and docetaxel [Taxotere]) and the protein kinase C activator gnidimacrin, are evaluated. Efforts under way to integrate these new compounds into clinical trials are discussed.
引用
收藏
页码：87 / 89
页数：3
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