RADIOTHERAPY Preoperative chemoradiotherapy for rectal cancer

被引：10

作者：

Roedel, Claus ^{[1
]}

机构：

[1] Goethe Univ Frankfurt, Dept Radiotherapy & Oncol, D-60590 Frankfurt, Germany

来源：

NATURE REVIEWS CLINICAL ONCOLOGY | 2010年 / 7卷 / 03期

关键词：

POSTOPERATIVE CHEMORADIOTHERAPY; ADJUVANT THERAPY; RANDOMIZED-TRIAL;

D O I：

10.1038/nrclinonc.2010.10

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chemoradiotherapy and surgical resection are important elements of multimodality treatment for patients with locally advanced rectal cancer. The optimum sequence of these modalities has been addressed in several randomized trials and preoperative chemoradiotherapy has been shown to be superior to postoperative treatment for a variety of end points.

引用

页码：129 / 130

页数：2

共 9 条

[1]

[Anonymous], JAMA

[2] PREOPERATIVE OR POSTOPERATIVE IRRADIATION IN ADENOCARCINOMA OF THE RECTUM - FINAL TREATMENT RESULTS OF A RANDOMIZED TRIAL AND AN EVALUATION OF LATE SECONDARY EFFECTS [J].

FRYKHOLM, GJ ;

GLIMELIUS, B ;

PAHLMAN, L .

DISEASES OF THE COLON & RECTUM, 1993, 36 (06) :564-572

[3]

*GASTR TUM STUD GR, 1985, NEW ENGL J MED, V312, P465

[4] A systematic overview of radiation therapy effects in rectal cancer [J].

Glimelius, B ;

Grönberg, H ;

Järhult, J ;

Wallgren, A ;

Cavallin-Ståhl, E .

ACTA ONCOLOGICA, 2003, 42 (5-6) :476-492

[5] EFFECTIVE SURGICAL ADJUVANT THERAPY FOR HIGH-RISK RECTAL-CARCINOMA [J].

KROOK, JE ;

MOERTEL, CG ;

GUNDERSON, LL ;

WIEAND, HS ;

COLLINS, RT ;

BEART, RW ;

KUBISTA, TP ;

POON, MA ;

MEYERS, WC ;

MAILLIARD, JA ;

TWITO, DI ;

MORTON, RF ;

VEEDER, MH ;

WITZIG, TE ;

CHA, S ;

VIDYARTHI, SC .

NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (11) :709-715

[6] Integration of novel agents into combined-modality treatment for rectal cancer patients [J].

Roedel, Claus ;

Sauer, Rolf .

STRAHLENTHERAPIE UND ONKOLOGIE, 2007, 183 (05) :227-235

[7] Preoperative Multimodality Therapy Improves Disease-Free Survival in Patients With Carcinoma of the Rectum: NSABP R-03 [J].

Roh, Mark S. ;

Colangelo, Linda H. ;

O'Connell, Michael J. ;

Yothers, Greg ;

Deutsch, Melvin ;

Allegra, Carmen J. ;

Kahlenberg, Morton S. ;

Baez-Diaz, Luis ;

Ursiny, Carol S. ;

Petrelli, Nicholas J. ;

Wolmark, Norman .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (31) :5124-5130

[8] Preoperative versus postoperative chemoradiotherapy for rectal cancer [J].

Sauer, R ;

Becker, H ;

Hohenberger, W ;

Rodel, C ;

Wittekind, C ;

Fietkau, R ;

Martus, P ;

Tschmelitsch, J ;

Hager, E ;

Hess, CF ;

Karstens, JH ;

Liersch, T ;

Schmidberger, H ;

Raab, R .

NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (17) :1731-1740

[9] Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial [J].

Sebag-Montefiore, David ;

Stephens, Richard J. ;

Steele, Robert ;

Monson, John ;

Grieve, Robert ;

Khanna, Subhash ;

Quirke, Phil ;

Couture, Jean ;

de Metz, Catherine ;

Myint, Arthur Sun ;

Bessell, Eric ;

Griffiths, Gareth ;

Thompson, Lindsay C. ;

Parmar, Mahesh .

LANCET, 2009, 373 (9666) :811-820

← 1 →