Atmospheric pressure ionization permanent magnet Fourier transform ion cyclotron resonance mass spectrometry

被引:14
|
作者
Vilkov, Andrey N.
Gamage, Chaminda M.
Misharin, Alexander S.
Doroshenko, Vladimir M.
Tolmachev, Dmitry A.
Tarasova, Irina A.
Kharybin, Oleg N.
Novoselov, Konstantin P.
Gorshkov, Michael V.
机构
[1] MassTech Inc, Columbia, MD 21046 USA
[2] Russian Acad Sci, Inst Energy Problems Chem Phys, Moscow V71, Russia
关键词
D O I
10.1016/j.jasms.2007.05.010
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A new Fourier transform ion cyclotron resonance mass spectrometer based on a permanent magnet with an atmospheric pressure ionization source was designed and constructed. A mass resolving power (full-width-at-half-maximum) of up to 80,000 in the electron ionization mode and 25,000 in the electrospray mode was obtained. Also, a mass measurement accuracy at low-ppm level has been demonstrated for peptide mixtures in a mass range of up to 1200 m/z in the isotopically resolved mass spectra.
引用
收藏
页码:1552 / 1558
页数:7
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