Controlled uptake and release of imatinib from ultrasound nanoparticles Cu3(BTC)2 metal-organic framework in comparison with bulk structure

被引：30

作者：

Abbasi, Amir Reza ^{[1
]}

Rizvandi, Maryam ^{[1
]}

Azadbakht, Azadeh ^{[2
]}

Rostamnia, Sadegh ^{[3
]}

机构：

[1] Razi Univ, Fac Chem, Kermanshah 67194, Iran

[2] Islamic Azad Univ, Khorramabad Branch, Dept Chem, Khorramabad, Iran

[3] Univ Maragheh, Dept Chem, ONG, POB 55181-83111, Maragheh, Iran

来源：

JOURNAL OF COLLOID AND INTERFACE SCIENCE | 2016年 / 471卷

基金：

美国国家科学基金会;

关键词：

Nanoparticles; Imatinib; Ultrasound; Metal-organic frameworks; ADSORPTION AFFINITY; HYDROGEN; STORAGE; FIBER;

D O I：

10.1016/j.jcis.2016.03.018

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The porosity of metal-organic frameworks (MOFs) is an important point concerning the possible use of such functional materials for different purposes. In this work, we study uptake and release properties of imatinib (IM) from nano Cu(lI)-MOF in comparison with bulk Cu(II)-MOF. To explore the absorption ability of the Cu(II)-MOF to IM, fresh sample of Cu-3(BTC)(2) was immersed in an aqueous solution of IM and were monitored in real time with UV/vis spectroscopy. Results show that the adsorbed quantity of IM over nano Cu-3(BTC)(2) (I) is much higher than those over a bulk Cu-3(BTC)(2) (II). (C) 2016 Published by Elsevier Inc.

引用

收藏

页码：112 / 117

页数：6

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