The Utility of Quantitative EEG in Detecting Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage

被引：15

作者：

Baang, Hae Young ^{[1
]}

Chen, Hsin Yi ^{[1
]}

Herman, Alison L. ^{[1
]}

Gilmore, Emily J. ^{[1
]}

Hirsch, Lawrence J. ^{[1
]}

Sheth, Kevin N. ^{[1
]}

Petersen, Nils H. ^{[1
]}

Zafar, Sahar F. ^{[2
]}

Rosenthal, Eric S. ^{[2
]}

Westover, M. Brandon ^{[2
]}

Kim, Jennifer A. ^{[1
]}

机构：

[1] Yale Univ, Dept Neurol, New Haven, CT 06510 USA

[2] Massachusetts Gen Hosp, Dept Neurol, Boston, MA 02114 USA

来源：

JOURNAL OF CLINICAL NEUROPHYSIOLOGY | 2022年 / 39卷 / 03期

关键词：

Quantitative electroencephalography; EEG; Delayed cerebral ischemia; Subarachnoid hemorrhage; Transcranial Doppler; Vasospasm; TRANSCRANIAL DOPPLER; SPREADING DEPOLARIZATION; BLOOD-FLOW; ANGIOGRAPHIC VASOSPASM; CEREBROSPINAL-FLUID; DOUBLE-BLIND; AUTOREGULATION; ACTIVATION; DEPRESSION; DIAGNOSIS;

D O I：

10.1097/WNP.0000000000000754

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In this review, we discuss the utility of quantitative EEG parameters for the detection of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage in the context of the complex pathophysiology of DCI and the limitations of current diagnostic methods. Because of the multifactorial pathophysiology of DCI, methodologies solely assessing blood vessel narrowing (vasospasm) are insufficient to detect all DCI. Quantitative EEG has facilitated the exploration of EEG as a diagnostic modality of DCI. Multiple quantitative EEG parameters such as alpha power, relative alpha variability, and alpha/delta ratio show reliable detection of DCI in multiple studies. Recent studies on epileptiform abnormalities suggest that their potential for the detection of DCI. Quantitative EEG is a promising, continuous, noninvasive, monitoring modality of DCI implementable in daily practice. Future work should validate these parameters in larger populations, facilitated by the development of automated detection algorithms and multimodal data integration.

引用

页码：207 / 215

页数：9

共 94 条

[1] Sustained NMDA receptor activation by spreading depolarizations can initiate excitotoxic injury in metabolically compromised neurons [J].