Eukaryotic transcription factors

被引：35
作者：
Tan, S [1 ]
Richmond, TJ [1 ]
机构：
[1] ETH Honggerberg, Inst Mol Biol & Biophys, CH-8093 Zurich, Switzerland
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1998年 / 8卷 / 01期
关键词：
D O I：
10.1016/S0959-440X(98)80008-0
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The structural characterization of eukaryotic transcription factors that interact with DNA has advanced on two fronts in the past two years. New complexes of transcription factors bound to TATA-box DNA include the TFIIA-TBP-DNA complex as well as human and archaeal TBP-DNA and TFIIB-TBP-DNA complexes, respectively. In addition, recent studies of proximal/distal promoter complexes demonstrate that DNA-binding motifs may be modified in nature by adding secondary structure elements to diversify DNA-binding specificities and affinities.
引用
收藏
页码：41 / 48
页数：8
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