N-Tosylhydrazones: versatile synthons in the construction of cyclic compounds

被引：310

作者：

Xia, Ying ^{[1
]}

Wang, Jianbo ^{[1
]}

机构：

[1] Peking Univ, BNLMS, Coll Chem, Key Lab Bioorgan Chem & Mol Engn,Minist Educ, Beijing 100871, Peoples R China

来源：

CHEMICAL SOCIETY REVIEWS | 2017年 / 46卷 / 08期

关键词：

GENERATED IN-SITU; PALLADIUM-CATALYZED INSERTION; TANDEM CYCLOADDITION REACTIONS; CARBENE MIGRATORY INSERTION; METAL-FREE CYCLOPROPANATION; CROSS-COUPLING REACTIONS; BOND FORMATION SYNTHESIS; AZIDE-FREE CONDITIONS; C-C BOND; DIAZO-COMPOUNDS;

D O I：

10.1039/c6cs00737f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

N-Tosylhydrazones have recently emerged as useful synthons in a variety of transition-metal-catalyzed and transition-metal-free reactions, which affords novel methodologies for the formation of carboncarbon and carbon-heteroatom bonds. In this context, it has been found that N-tosylhydrazones can be used as versatile building blocks in the construction of a range of cyclic compounds. In this review, cyclization reactions based on N-tosylhydrazones as substrates are discussed. A series of cyclic compounds, including aromatic and non-aromatic ring systems, are demonstrated to be easily constructed by cyclizations with N-tosylhydrazones.

引用

页码：2306 / 2362

页数：57

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