The current demographic scenario of the world shows that the population of developing countries is growing at an unprecedented rate with the increasing scarcity of freshwater resources. Therefore there is a great need to propose appropriate wastewater treatment in Such Countries to reuse wastewater. Wastewater treatment should not only target pathogens removal but also many compounds named endocrine disruptors (EDCs) which have not been included yet in reuse wastewater legislations. This paper provides information on the fate of EDCs in wastewater treatment, current wastewater legislations and it also summarizes a recently developed decision support tool for decision makers (wastewater technologists and risk analyzers) to improve their decision processes in respect to wastewater treatment and reuse schemes.