Increased IgE+ B Cells in Sputum, but Not Blood, Bone Marrow, or Tonsils, after Inhaled Allergen Challenge in Subjects with Asthma

被引：9

作者：

Oliveria, John-Paul ^{[1
]}

Salter, Brittany M. ^{[1
]}

MacLean, Jonathan ^{[1
]}

Kotwal, Shweta ^{[2
]}

Smith, Ashley ^{[2
]}

Harris, Jeffrey M. ^{[2
]}

Scheerens, Heleen ^{[2
]}

Sehmi, Roma ^{[1
]}

Gauvreau, Gail M. ^{[1
]}

机构：

[1] McMaster Univ, Hamilton, ON, Canada

[2] Genentech Inc, 460 Point San Bruno Blvd, San Francisco, CA 94080 USA

来源：

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2017年 / 196卷 / 01期

关键词：

PLASMA-CELLS;

D O I：

10.1164/rccm.201611-2274LE

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

引用

页码：107 / 109

页数：3

共 13 条

[11] Increases in allergen-specific IgE in BAL after segmental allergen challenge in atopic asthmatics [J].

Wilson, DR ;

Merrett, TG ;

Varga, EM ;

Smurthwaite, L ;

Gould, HJ ;

Kemp, M ;

Hooper, J ;

Till, SJ ;

Durham, SR .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 165 (01) :22-26

[12] IgE plus B cells are scarce, but allergen-specific B cells with a memory phenotype circulate in patients with allergic rhinitis [J].

Wong, K. J. ;

Timbrell, V. ;

Xi, Y. ;

Upham, J. W. ;

Collins, A. M. ;

Davies, J. M. .

ALLERGY, 2015, 70 (04) :420-428

[13] Targeting IgE production in mice and humans [J].

Wu, Lawren C. ;

Scheerens, Heleen .

CURRENT OPINION IN IMMUNOLOGY, 2014, 31 :8-15

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