Stereoselective synthesis of polyfunctionalized aziridines

被引：3
|
作者：
Troisi, Luigino
Granito, Catia
Pindinelli, Emanuela
Ronzini, Ludovico
机构：
[1] Univ Lecce, Dept Sci & Biol, I-73100 Lecce, Italy
[2] Univ Lecce, Dept Environm Technol, I-73100 Lecce, Italy
来源：
HETEROCYCLES | 2007年 / 71卷 / 06期
关键词：
D O I：
10.3987/COM-07-11045
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
1,2,3-triHeterocycle-substituted aziridines were prepared by coupling of (alpha-chioroalkyl) oxazolinyllithium compounds with diheteroaryl imines. The trapping by different electrophiles of the corresponding aziridinyl anions, generated by treatment with strong bases, was investigated. The stereoselectivity of the synthesis and the functionalization reactions was studied highlighting the different stabilizing effects of the heterocycle substituents.
引用
收藏
页码：1381 / +
页数：17
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