Useful agents against aflatoxin B1 - antibacterial azomethine and Mn(III) complexes involving L-Threonine, L-Serine, and L-Tyrosine

被引：11

作者：

Anar, Mustafa ^{[1
]}

Ozkan, Elvan Hasanoglu ^{[2
]}

Ogutcu, Hatice ^{[3
]}

Agar, Guleray ^{[1
]}

Sakiyan, Iffet ^{[4
]}

Sari, Nursen ^{[2
]}

机构：

[1] Ataturk Univ, Dept Mol Biol & Genet, Erzurum, Turkey

[2] Gazi Univ, Dept Chem, Ankara, Turkey

[3] Ahi Evran Univ, Dept Biol, Kirsehir, Turkey

[4] Ankara Univ, Dept Chem, TR-06100 Ankara, Turkey

来源：

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY | 2016年 / 44卷 / 03期

关键词：

antimicrobial properties; aflatoxin B; Mn(III) complexes; mutagenicity; AMINO-ACIDS; EPOXIDATION; GLUTAMINE;

D O I：

10.3109/21691401.2014.991792

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The present study is focused on evaluating the antimutagenic properties of Schiff bases and Mn(III) complexes with L-Threonine, L-Serine and L-Tyrosine, which have antimicrobial activity. These six compounds were investigated for antimutagenic properties against Aflatoxin B (AFB) by the micronucleus (MN) assay in a human lymphocyte cell culture in vitro. The protective role of these compounds against AFB-induced MN is probably related to its doses. A mechanism has been proposed to reduce the effect of AFB.

引用

页码：853 / 858

页数：6

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