Melatonin: a "Higgs boson'' in human reproduction

被引:28
作者
Dikic, Svetlana Dragojevic [1 ,2 ]
Jovanovic, Ana Mitrovic [1 ,2 ]
Dikic, Srdjan [2 ,3 ]
Jovanovic, Tomislav [2 ,4 ]
Jurisic, Aleksandar [1 ,2 ]
Dobrosavljevic, Aleksandar [1 ]
机构
[1] Univ Belgrade, Dept Obstet & Gynecol Narodni Front, Belgrade 11050, Serbia
[2] Univ Belgrade, Fac Med, Belgrade 11050, Serbia
[3] Univ Med Ctr Bezanijska Kosa, Belgrade, Serbia
[4] Clin Ctr Serbia, Inst Physiol, Belgrade, Serbia
关键词
Cancer; immune function; melatonin; reproductive function; reproductive health; BREAST-CANCER; OXIDATIVE STRESS; SERUM MELATONIN; REACTIVE OXYGEN; IN-VITRO; SUPRACHIASMATIC NUCLEUS; PREMENOPAUSAL WOMEN; EXOGENOUS MELATONIN; PINEAL MELATONIN; MENOPAUSAL WOMEN;
D O I
10.3109/09513590.2014.978851
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
As the Higgs boson could be a key to unlocking mysteries regarding our Universe, melatonin, a somewhat mysterious substance secreted by the pineal gland primarily at night, might be a crucial factor in regulating numerous processes in human reproduction. Melatonin is a powerful antioxidant which has an essential role in controlling several physiological reactions, as well as biological rhythms throughout human reproductive life. Melatonin, which is referred to as a hormone, but also as an autocoid, a chronobiotic, a hypnotic, an immunomodulator and a biological modifier, plays a crucial part in establishing homeostatic, neurohumoral balance and circadian rhythm in the body through synergic actions with other hormones and neuropeptides. This paper aims to analyze the effects of melatonin on the reproductive function, as well as to shed light on immunological and oncostatic properties of one of the most powerful hormones.
引用
收藏
页码:92 / 101
页数:10
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