Characterization of glycerol phosphate oxidase from Streptococcus pneumoniae and its application for ketose synthesis

被引：8

作者：

Li, Zijie ^{[1
,2
]}

Qiao, Yingxin ^{[2
]}

Cai, Li ^{[3
]}

Nakanishi, Hideki ^{[2
]}

Gao, Xiao-Dong ^{[2
]}

机构：

[1] Jiangnan Univ, Sch Biotechnol, Minist Educ, Key Lab Ind Biotechnol, Wuxi 214122, Peoples R China

[2] Jiangnan Univ, Sch Biotechnol, Minist Educ, Key Lab Carbohydrate Chem & Biotechnol, Wuxi 214122, Peoples R China

[3] Univ South Carolina Salkehatchie, Div Math & Sci, Walterboro, SC 29488 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2015年 / 25卷 / 03期

基金：

中国博士后科学基金; 中国国家自然科学基金;

关键词：

Glycerol phosphate oxidase; Aldolase; Enzymatic synthesis; Rare sugar; Streptococcus pneumoniae; ALPHA-GLYCEROPHOSPHATE OXIDASE; C BOND FORMATION; DIHYDROXYACETONE PHOSPHATE; ORGANIC-SYNTHESIS; ALDOLASE RHAD; ENZYMES; SUGARS;

D O I：

10.1016/j.bmcl.2014.12.032

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Glycerol phosphate oxidase from Streptococcus pneumoniae (GPO(S.pne)) was purified and characterized. By the actions of GPO(S.pne) and dihydroxyacetone phosphate (DHAP)-dependent aldolases, various ketoses including rare sugars were synthesized with glyceraldehydes as acceptors in a one-pot four-enzyme system. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：504 / 507

页数：4

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