Epigenetics and transcription regulation during eukaryotic diversification: the saga of TFIID

被引：27

作者：

Antonova, Simona, V ^{[1
]}

Boeren, Jeffrey ^{[2
]}

Timmers, H. T. Marc ^{[1
,3
,4
]}

Snel, Berend ^{[5
]}

机构：

[1] Univ Med Ctr Utrecht, Mol Canc Res & Regenerat Med, NL-3584 CT Utrecht, Netherlands

[2] Erasmus MC, Dept Dev Biol, NL-3015 CN Rotterdam, Netherlands

[3] Univ Freiburg, Med Ctr, Dept Urol, D-79106 Freiburg, Germany

[4] Deutsch Krebsforsch Zentrum DKFZ, Deutsch Konsortium Translat Krebsforsch DKTK Stan, D-69120 Heidelberg, Germany

[5] Univ Utrecht, Dept Biol, Theoret Biol & Bioinformat, NL-3584 CH Utrecht, Netherlands

来源：

GENES & DEVELOPMENT | 2019年 / 33卷 / 15-16期

关键词：

basal transcription; phylogenetic analyses; SAGA; TFIID; GENE-EXPRESSION; HISTONE FOLD; COMPLEX; DOMAIN; DIVERGENCE; TAF(II)250; CHROMATIN; TAF1-TAF7; SELECTION; INSIGHTS;

D O I：

10.1101/gad.300475.117

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The basal transcription factor TFIID is central for RNA polymerase II-dependent transcription. Human TFIID is endowed with chromatin reader and DNA-binding domains and protein interaction surfaces. Fourteen TFIID TATA-binding protein (TBP)-associated factor (TAF) subunits assemble into the holocomplex, which shares subunits with the Spt-Ada-Gcn5-acetyltransferase (SAGA) coactivator. Here, we discuss the structural and functional evolution of TFIID and its divergence from SAGA. Our orthologous tree and domain analyses reveal dynamic gains and losses of epigenetic readers, plant-specific functions of TAF1 and TAF4, the HEAT2-like repeat in TAF2, and, importantly, the pre-LECA origin of TFIID and SAGA. TFIID evolution exemplifies the dynamic plasticity in transcription complexes in the eukaryotic lineage.

引用

页码：888 / 902

页数：15

共 70 条

[11] Abnormal sperm in mice lacking the Taf7l gene [J].

Cheng, Yong ;

Buffone, Mariano G. ;

Kouadio, Martin ;

Goodheart, Mary ;

Page, David C. ;

Gerton, George L. ;

Davidson, Irwin ;

Wang, Peijing Jeremy .

MOLECULAR AND CELLULAR BIOLOGY, 2007, 27 (07) :2582-2589

[12] Zinc knuckle of TAF1 is a DNA binding module critical for TFIID promoter occupancy [J].

Curran, Elizabeth C. ;

Wang, Hui ;

Hinds, Thomas R. ;

Zheng, Ning ;

Wang, Edith H. .

SCIENTIFIC REPORTS, 2018, 8

[13] Shifting Players and Paradigms in Cell-Specific Transcription [J].

D'Alessio, Joseph A. ;

Wright, Kevin J. ;

Tjian, Robert .

MOLECULAR CELL, 2009, 36 (06) :924-931

[14] Marsupial Genome Sequences: Providing Insight into Evolution and Disease [J].

Deakin, Janine E. .

SCIENTIFICA, 2012, 2012

[15] M1 aminopeptidases as drug targets: broad applications or therapeutic niche? [J].

Drinkwater, Nyssa ;

Lee, Jisook ;

Yang, Wei ;

Malcolm, Tess R. ;

McGowan, Sheena .

FEBS JOURNAL, 2017, 284 (10) :1473-1488

[16] Compatibility with Killer Explains the Rise of RNAi-Deficient Fungi [J].

Drinnenberg, Ines A. ;

Fink, Gerald R. ;

Bartel, David P. .

SCIENCE, 2011, 333 (6049) :1592-1592

[17] SPT3 INTERACTS WITH TFIID TO ALLOW NORMAL TRANSCRIPTION IN SACCHAROMYCES-CEREVISIAE [J].

EISENMANN, DM ;

ARNDT, KM ;

RICUPERO, SL ;

ROONEY, JW ;

WINSTON, F .

GENES & DEVELOPMENT, 1992, 6 (07) :1319-1331

[18] The Pfam protein families database: towards a more sustainable future [J].

Finn, Robert D. ;

Coggill, Penelope ;

Eberhardt, Ruth Y. ;

Eddy, Sean R. ;

Mistry, Jaina ;

Mitchell, Alex L. ;

Potter, Simon C. ;

Punta, Marco ;

Qureshi, Matloob ;

Sangrador-Vegas, Amaia ;

Salazar, Gustavo A. ;

Tate, John ;

Bateman, Alex .

NUCLEIC ACIDS RESEARCH, 2016, 44 (D1) :D279-D285

[19] TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9 [J].

Frontini, M ;

Soutoglou, E ;

Argentini, M ;

Bole-Feysot, C ;

Jost, B ;

Scheer, E ;

Tora, L .

MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (11) :4638-4649

[20] The histone fold is a key structural motif of transcription factor TFIID [J].

Gangloff, YG ;

Romier, C ;

Thuault, S ;

Werten, S ;

Davidson, I .

TRENDS IN BIOCHEMICAL SCIENCES, 2001, 26 (04) :250-257

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