Stress hormones and eating disorders

被引：44

作者：

Chami, Rayane ^{[1
]}

Monteleone, Alessio Maria ^{[2
]}

Treasure, Janet ^{[1
]}

Monteleone, Palmiero ^{[2
]}

机构：

[1] Kings Coll London, Dept Psychol Med, Sect Eating Disorders, 103 Denmark Hill, London SE5 8AF, England

[2] Univ Naples SUN, Dept Psychiat, Naples, Italy

来源：

MOLECULAR AND CELLULAR ENDOCRINOLOGY | 2019年 / 497卷

关键词：

CORTISOL AWAKENING RESPONSE; PITUITARY-ADRENAL-AXIS; EARLY-LIFE STRESS; DEXAMETHASONE-SUPPRESSION TEST; SALIVARY ALPHA-AMYLASE; ANOREXIA-NERVOSA; BULIMIA-NERVOSA; CHILDHOOD MALTREATMENT; DNA METHYLATION; BRAIN;

D O I：

10.1016/j.mce.2018.12.009

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Aims: The aim of this paper is to emphasize the role of stress processes in the aetiology of eating disorders. Methods: We have examined the literature for evidence that people with eating disorders might exhibit markers of stress and show signs of the "maltreated ecophenotype". Results: Early adversity is more common among people with binge eating behaviours. The secondary effects of malnutrition, which are mostly marked in anorexia nervosa, may be an added stressor that could also contribute to the stress related phenotype. People with eating disorders have anomalies in brain structure, reward and punishment sensitivity, and the balance between HPA and SMA function. These may be potential targets for treatment.

引用

页数：7

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