Highly Efficient and Catalyst-Free Synthesis of Benzimidazoles in Aqueous Media

被引：1

作者：

Zhou, L. -H. ^{[1
]}

Jin, Y. -J. ^{[1
]}

Ma, L. -F. ^{[1
]}

Huang, W. -H. ^{[1
]}

Wu, Y. ^{[1
]}

机构：

[1] Nanchang Ctr Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Jiangxi Provincal Key Lab Anim Origin & Vector Bo, Phys & Chem Dept,Collaborat Unit Field Epidemiol, Nanchang 330038, Jiangxi, Peoples R China

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 57卷 / 05期

关键词：

catalysts-free; o-phenylenediamine; thiourea dioxide; benzimidazoles; water; 2-SUBSTITUTED BENZIMIDAZOLE; QUINOXALINES; DERIVATIVES;

D O I：

10.1134/S1070428021050092

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient and highly efficient, catalysts-free synthesis of benzimidazoles in an aqueous medium has been developed. The conditions of the synthesis were optimized, and its scope was successfully extended to various substrates with good to excellent yields. The experimental procedure is simple, and the products can be isolated by filtration followed by recrystallization from water.

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收藏

页码：825 / 830

页数：6

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