Chemical structures of constituents from the flowers of Osmanthus fragrans var. aurantiacus

被引:32
作者
Liu, Jiang [1 ]
Nakamura, Seikou [2 ]
Xu, Bin [2 ]
Matsumoto, Takahiro [2 ]
Ohta, Tomoe [2 ]
Fujimoto, Katsuyoshi [2 ]
Ogawa, Keiko [2 ]
Fukaya, Masashi [2 ]
Miyake, Shiori [2 ]
Yoshikawa, Masayuki [2 ]
Matsuda, Hisashi [2 ]
机构
[1] Sichuan Agr Univ, Minist Agr, Key Lab Crop Ecophysiol & Farming Syst Southwest, Chengdu 611130, Peoples R China
[2] Kyoto Pharmaceut Univ, Dept Pharmacognosy, Yamashina Ku, Kyoto 6078412, Japan
关键词
Osmanthus fragrans var. aurantiacus; Floraosmanoside; Floraosmanolactone; Megastigmane; gamma-Decalactone; Medicinal flower; NITRIC-OXIDE PRODUCTION; ACYLATED SUCROSES; PRUNUS-MUME; FRAXINUS-EXCELSIOR; PHENOLIC-COMPOUNDS; CAMELLIA-JAPONICA; ALDOSE REDUCTASE; CANANGA-ODORATA; BUDS; MELANOGENESIS;
D O I
10.1007/s11418-014-0869-1
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Three new megastigmane glycosides named floraosmanosides I-III and a new gamma-decalactone named floraosmanolactone I together with 16 known constituents were isolated from the flowers of Osmanthus fragrans var. aurantiacus cultivated in Guangxi Zhuang Autonomous Region, China. The chemical structures of the new compounds were elucidated on the basis of chemical and physicochemical evidence. Among them, ligustroside and (+)-pinoresinol significantly inhibited nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophages.
引用
收藏
页码:135 / 141
页数:7
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