Recent Developments in Pd0-Catalyzed Alkene-Carboheterofunctionalization Reactions

被引：115

作者：

Garlets, Zachary J. ^{[1
]}

White, Derick R. ^{[1
]}

Wolfe, John P. ^{[1
]}

机构：

[1] Univ Michigan, Dept Chem, 930 N Univ Ave, Ann Arbor, MI 48109 USA

来源：

ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 6卷 / 06期

关键词：

alkenes; carbocycles; heterocycles; palladium; synthetic methods; ENANTIOSELECTIVE TOTAL-SYNTHESIS; PD-CATALYZED CARBOAMINATION; ASYMMETRIC TOTAL-SYNTHESIS; NATURAL-PRODUCT SYNTHESIS; STEREOCONTROLLED SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; MIGRATORY INSERTION; ALDER REACTIONS; MILD CONDITIONS; WACKER REACTION;

D O I：

10.1002/ajoc.201600577

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This Focus Review summarizes recent developments in palladium-catalyzed alkene carboalkoxylation and carboamination reactions. New synthetic methods that have been reported within the past four years are described, along with mechanistic insights and the influence of reaction mechanism on product stereochemistry. The applications of these transformations to the synthesis of natural products and other biologically relevant compounds are also discussed.

引用

页码：636 / 653

页数：18

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