Fluorination of thiocarbonyl compounds with bis(2-methoxyethyl)aminosulfur trifluoride (deoxo-fluor reagent):: A facile synthesis of gem-difluorides

被引：54

作者：

Lal, GS ^{[1
]}

Lobach, E ^{[1
]}

Evans, A ^{[1
]}

机构：

[1] Air Prod & Chem Inc, Allentown, PA 18195 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2000年 / 65卷 / 16期

关键词：

D O I：

10.1021/jo000020j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A variety of thiocarbonyl derivatives (thioketone, thioester, thioamide, dithioester, and dithiocarbamate) were converted to the corresponding gem-difluorides in excellent yields on reaction with the fluorinating agent, bis(2-methoxyethyl)aminosulfur trifluoride, in the presence of SbCl3.

引用

页码：4830 / 4832

页数：3

共 35 条

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[2]

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[3]

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