Periarticular Injection After Total Knee Arthroplasty Using Liposomal Bupivacaine vs a Modified Ranawat Suspension: A Prospective, Randomized Study

被引：59

作者：

Collis, Philip N. ^{[1
]}

Hunter, Allison M. ^{[1
]}

Vaughn, Michael D. Derek ^{[1
]}

Carreon, Leah Y. ^{[2
]}

Huang, Jiapeng ^{[3
]}

Malkani, Arthur L. ^{[4
]}

机构：

[1] Univ Louisville, Dept Orthopaed Surg, Louisville, KY 40292 USA

[2] Norton Leatherman Spine Ctr, Louisville, KY USA

[3] Jewish Hosp, Louisville, KY USA

[4] Univ Louisville, Adult Reconstruct Program, 550 S Jackson St,1st Floor,ACB, Louisville, KY 40292 USA

来源：

JOURNAL OF ARTHROPLASTY | 2016年 / 31卷 / 03期

关键词：

liposomal bupivacaine; TKA; postop pain; ranawat suspension; EXTENDED-RELEASE BUPIVACAINE; INJECTABLE SUSPENSION; ANALGESIA PROTOCOL; POSTOPERATIVE PAIN; EFFICACY; EVENTS; BURDEN; LENGTH; HCL;

D O I：

10.1016/j.arth.2015.09.025

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Background: The purpose of this study is to compare liposomal bupivacaine to a modified (Ranawat) local injection for total knee arthroplasty (TKA). Methods: This is a prospective, randomized study of 105 consecutive patients undergoing primary TKA. Group A patients received a periarticular injection with liposomal bupivacaine and group B with a mixture of ropivacaine, epinephrine, ketorolac, and clonidine. There were 54 patients in the group A (liposomal bupivacaine) and 51 in group B. Results: There were no differences in the groups with respect to age, sex, and preoperative knee scores. There were no differences with respect to postoperative narcotic usage and knee range of motion. Conclusion: Liposomal bupivacaine as a periarticular injection after TKA demonstrated similar pain levels, narcotic usage, and range of motion compared to a modified Ranawat suspension but improved walking distance. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：633 / 636

页数：4

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